Reactome | BRPF3 [cytosol]

BRPF3 [cytosol]

Stable Identifier

R-HSA-350716

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Bromodomain and PHD finger-containing protein 3

Locations in the PathwayBrowser

Expand all

Hemostasis (Homo sapiens)

- Platelet activation, signaling and aggregation (Homo sapiens)
  - Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
    - Platelet degranulation (Homo sapiens)
      - Release of platelet cytosolic components (Homo sapiens)
        
        Platelet releasate cytosolic proteins [cytosol] (Homo sapiens)
        
        BRPF3 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9ULD4 BRPF3

Gene Names

BRPF3, KIAA1286

Chain

chain:1-1205

Reference Genes

BioGPS Gene:27154 Q9ULD42

COSMIC (genes):BRPF3 BRPF3

CTD Gene:27154 BRPF3

dbSNP Gene:27154 BRPF3

ENSEMBL:ENSG00000096070 BRPF3

HGNC:14256 Q9ULD42

KEGG:hsa:27154 Q9ULD42

Monarch:27154 Q9ULD42

NCBI Gene:27154 Q9ULD42

UCSC:Q9ULD4 Q9ULD42

Reference Transcript

Participates

as a member of

Platelet releasate cytosolic proteins [cytosol] (Homo sapiens)

Other forms of this molecule

BRPF3 [extracellular region]

BRPF3 [nucleoplasm]

Inferred To

lin-49 [cytosol] (Caenorhabditis elegans)

nto1 [cytosol] (Schizosaccharomyces pombe)

NTO1 [cytosol] (Saccharomyces cerevisiae)

Br140 [cytosol] (Drosophila melanogaster)

BRPF3 [cytosol] (Bos taurus)

BRPF3 [cytosol] (Canis familiaris)

BRPF3 [cytosol] (Dictyostelium discoideum)

BRPF3 [cytosol] (Gallus gallus)

BRPF3 [cytosol] (Sus scrofa)

Brpf3 [cytosol] (Mus musculus)

Brpf3 [cytosol] (Rattus norvegicus)

brpf3 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_056510.2, XP_005249067.1, XP_005249068.1, XP_047274605.1, XP_011512791.1

Guide to Pharmacology - Targets

2731

ENSEMBL

ENST00000339717, ENSP00000345419, ENSP00000350267, ENST00000357641, ENSP00000434501, ENSG00000096070, ENST00000534694

OpenTargets

ENSG00000096070

GeneCards

BRPF3

HPA

ENSG00000096070-BRPF3

ZINC - Substances

BRPF3_HUMAN

ZINC target

Q9ULD4

PRO

Q9ULD4

Pharos - Targets

Q9ULD4

PDB

3PFS

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q16236 NFE2L2	13	p-S40-NFE2L2 [nucleoplasm] (R-HSA-9715109) p-S,T-NFE2L2 [nucleoplasm] (R-HSA-9715110) p-S40-NFE2L2 [cytosol] (R-HSA-8932290) p-S,T-NFE2L2 [cytosol] (R-HSA-8932311) NFE2L2 [cytosol] (R-HSA-201566) p-S,T-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760033) p-S40-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760018) ub-NFE2L2 [cytosol] (R-HSA-9758077) ub-p-S335, S338,T-NFE2L2 [nucleoplasm] (R-HSA-9762055) ub-p-S40, S335, S338- NFE2L2 [nucleoplasm] (R-HSA-9762058) p-S344, S347,T-NFE2L2 [nucleoplasm] (R-HSA-9762048) p-S40, S344, S347- NFE2L2 [nucleoplasm] (R-HSA-9762050) p-S,T,S558-NFE2L2 [nucleoplasm] (R-HSA-9795736)	0.508	3

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