Reactome | GSTT2B [cytosol]

GSTT2B [cytosol]

Stable Identifier

R-HSA-3302073

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Glutathione S-transferase theta-2B ecNumber2.5.1.18/ecNumber, GSTT2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P0CG30 GSTT2B

Gene Names

GSTT2B, GSTT2

Chain

initiator methionine:1, chain:2-244

Reference Genes

BioGPS Gene:653689 GSTT2B

COSMIC (genes):GSTT2B GSTT2B

CTD Gene:653689 GSTT2B

dbSNP Gene:653689 GSTT2B

ENSEMBL:ENSG00000133433 GSTT2B

ENSEMBL:ENSG00000133433.11 GSTT2B

ENSEMBL:ENSG00000278695.1 GSTT2B

HGNC:33437 GSTT2B

KEGG Gene (Homo sapiens):653689 GSTT2B

Monarch:653689 GSTT2B

NCBI Gene:653689 GSTT2B

UCSC:P0CG30 GSTT2B

Reference Transcript

RefSeq:NM_001080843.3 GSTT2B

Other Identifiers

1099_s_at

11722903_s_at

16928115

16933088

205439_PM_at

205439_at

3939650

3939651

3939654

3939660

3939661

3939662

3939663

3939664

3939665

3939666

3955032

3955033

3955034

3955035

3955036

3955037

3955038

3955040

3955041

653689

8071809

8074962

A_23_P109427

A_23_P357571

A_33_P3289045

GE58239

GO:0003824

GO:0004364

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006575

GO:0006749

GO:0006790

GO:0016740

GO:0043226

GO:0070062

HMNXSV003002660

ILMN_1789418

ILMN_2355549

L38503_at

PH_hs_0027035

TC22000142.hg

TC22000580.hg

g7669495_3p_at

Participates

as a component of

GSTT2B dimer [cytosol] (Homo sapiens)

Inferred To

GstT3 [cytosol] (Drosophila melanogaster)

Homologues of GSTT2B [cytosol] (Danio rerio)

Homologues of GSTT2B [cytosol] (Dictyostelium discoideum)

Homologues of GSTT2B [cytosol] (Drosophila melanogaster)

Homologues of GSTT2B [cytosol] (Gallus gallus)

Homologues of GSTT2B [cytosol] (Rattus norvegicus)

Homologues of GSTT2B [cytosol] (Xenopus tropicalis)

GstT2 [cytosol] (Drosophila melanogaster)

GstT4 [cytosol] (Drosophila melanogaster)

GSTT2B [cytosol] (Canis familiaris)

GSTT2B [cytosol] (Danio rerio)

GSTT2B [cytosol] (Dictyostelium discoideum)

GSTT2B [cytosol] (Gallus gallus)

GSTT2B [cytosol] (Mus musculus)

GSTT2B [cytosol] (Rattus norvegicus)

GSTT2B [cytosol] (Xenopus tropicalis)

gstt1 [cytosol] (Xenopus tropicalis)

cb870 [cytosol] (Danio rerio)

GstT1 [cytosol] (Drosophila melanogaster)

gstt1-like.2 [cytosol] (Xenopus tropicalis)

GSTT1L [cytosol] (Gallus gallus)

Cross References

RefSeq

NP_001074312.1

OpenTargets

ENSG00000133433

HPA

ENSG00000133433-GSTT2B

GeneCards

P0CG30

Ensembl

ENST00000616938, ENSP00000478389, ENSG00000278695, ENSP00000290765, ENST00000290765, ENSG00000133433

PRO

P0CG30

Pharos - Targets

P0CG30

HMDB Protein

HMDBP11755

PDB

1LJR, 4MPG, 2LJR, 3LJR

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.508	4

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