TRPs transport extracellular Ca2+ to cytosol

Stable Identifier
R-HSA-3295579
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
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All functionally characterized TRP channels are permeable to the divalent cation Ca2+ except TRPM4 and 5 (Latorre et al. 2009, Wu et al. 2010).

Literature References
PubMed ID Title Journal Year
20716668 International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family

Wu, LJ, Sweet, TB, Clapham, DE

Pharmacol. Rev. 2010
20025796 Structure-functional intimacies of transient receptor potential channels

Latorre, R, Zaelzer, C, Brauchi, S

Q. Rev. Biophys. 2009
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
calcium channel activity of TRPs [plasma membrane]
Physical Entity
Activity
This event is regulated
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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