Translation of p16INK4A mRNA is inhibited by miR-24

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R-HSA-3209114
Type
Reaction [omitted]
Species
Homo sapiens
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MicroRNA miR-24 inhibits translation of p16INK4A mRNA without causing mRNA degradation. This results in high p16INK4A transcript level accompanied by low p16INK4A protein level (Lal et al. 2008).

Literature References
PubMed ID Title Journal Year
18365017 p16(INK4a) translation suppressed by miR-24

Lal, A, Kim, HH, Abdelmohsen, K, Kuwano, Y, Pullmann, R, Srikantan, S, Subrahmanyam, R, Martindale, JL, Yang, X, Ahmed, F, Navarro, F, Dykxhoorn, D, Lieberman, J, Gorospe, M

PLoS ONE 2008
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