Unknown protease degrades GIF:Cbl to release Cbl

Stable Identifier
R-HSA-3000243
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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In the lysosome, gastric intrinsic factor (GIF) bound to cobalamin (Cbl) is degraded by an unknown protease to release Cbl (Fyfe et al. 2004).

Literature References
PubMed ID Title Journal Year
14576052 The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless

Fyfe, JC, Madsen, M, Højrup, P, Christensen, EI, Tanner, SM, de la Chapelle, A, He, Q, Moestrup, SK

Blood 2004
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
peptidase activity of unknown protease [lysosomal lumen]
Physical Entity
Activity
Authored
Reviewed
Created