BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins

Stable Identifier
R-HSA-2995376
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, chromosome, nuclear envelope
ReviewStatus
5/5
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BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins
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In late anaphase/early telophase, the separated sister chromatids usually coalesce into a single "chromatin disc". At the surface of the chromatin disc, there is an accumulation of dephosphorylated BANF1 (BAF) (Kaufmann et al. 2016), as well as proteins EMD (emerin), TMPO (LAP2beta), LEMD3 (MAN1), LEMD2 (LEM2) and lamins (Haraguchi et al. 2008, Asencio et al. 2012). Collectively, these interactions promote enclosure of the separated sister chromatids with nuclear membranes (Anderson et al. 2009).
Literature References
PubMed ID Title Journal Year
27875273 SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation

Kostrhon, S, Kukolj, E, Opravil, S, Slade, D, Brachner, A, Kaufmann, T, Mechtler, K, Beltzung, E, Hudecz, O, Bruno, M, Warren, G

J. Cell. Sci. 2016
18628300 Live cell imaging and electron microscopy reveal dynamic processes of BAF-directed nuclear envelope assembly

Hiraoka, Y, Haraguchi, T, Osakada, H, Koujin, T, Mori, C, Kojidani, T, Shimi, T, Yamamoto, A

J. Cell. Sci. 2008
19620630 Recruitment of functionally distinct membrane proteins to chromatin mediates nuclear envelope formation in vivo

Hetzer, MW, Hsiao, JP, Vargas, JD, Anderson, DJ

J. Cell Biol. 2009
22770216 Coordination of kinase and phosphatase activities by Lem4 enables nuclear envelope reassembly during mitosis

Wallenfang, MR, Mall, M, Davidson, IF, Santarella-Mellwig, R, Ly-Hartig, TB, Asencio, C, Gorjánácz, M, Mattaj, IW

Cell 2012
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Orthologous Events
BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Bos taurus)
BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Canis familiaris)
BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Mus musculus)
BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Rattus norvegicus)
BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Sus scrofa)
Authored
Orlic-Milacic, M  (2013-01-23)
Reviewed
Mattaj, IW  (2013-01-30)
Gorjánácz, M  (2013-01-30)
Created
Orlic-Milacic, M  (2013-01-22)
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