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CASQ2 [sarcoplasmic reticulum membrane]
Stable Identifier
R-HSA-2855225
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
sarcoplasmic reticulum membrane
Synonyms
Calsequestrin-2, CASQ2_HUMAN
Locations in the PathwayBrowser
Expand all
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Ion homeostasis (Homo sapiens)
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Homo sapiens)
RYR tetramer:FKBP1B tetramer:CASQ polymer:TRDN:junctin [sarcoplasmic reticulum membrane] (Homo sapiens)
CASQ polymer [sarcoplasmic reticulum lumen] (Homo sapiens)
CASQ2 polymer [sarcoplasmic reticulum lumen] (Homo sapiens)
CASQ2 [sarcoplasmic reticulum membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Homo sapiens)
RYR tetramer:FKBP1B tetramer:CASQ polymer:TRDN:junctin [sarcoplasmic reticulum membrane] (Homo sapiens)
CASQ polymer [sarcoplasmic reticulum lumen] (Homo sapiens)
CASQ2 polymer [sarcoplasmic reticulum lumen] (Homo sapiens)
CASQ2 [sarcoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O14958 CASQ2
Gene Names
CASQ2
Chain
signal peptide:1-19, chain:20-399
Reference Genes
BioGPS Gene:845 CASQ2
COSMIC (genes):CASQ2 CASQ2
CTD Gene:845 CASQ2
dbSNP Gene:845 CASQ2
ENSEMBL:ENSG00000118729 CASQ2
HGNC:1513 CASQ2
KEGG:hsa:845 CASQ2
Monarch:845 CASQ2
NCBI Gene:845 CASQ2
OMIM:114251 CASQ2
UCSC:O14958 CASQ2
Reference Transcript
RefSeq:NM_001232.3 CASQ2
Other Identifiers
11723223_at
11736412_s_at
11751361_a_at
16691333
207317_PM_s_at
207317_s_at
214497_3p_s_at
214497_PM_s_at
214497_s_at
2429557
2429558
2429559
2429560
2429561
2429562
2429563
2429564
2429565
2429567
2429568
2429569
2429575
2429580
2429581
2429583
2429584
2429585
2429587
2429588
2429593
2429597
2429598
2429599
2429600
2429605
2429606
2429608
2429612
2429618
2429619
2429620
2429621
36505_at
7918878
845
A_23_P126582
A_23_P412491
A_33_P3374258
GE57263
GO:0002027
GO:0003012
GO:0005509
GO:0005513
GO:0005515
GO:0005737
GO:0005783
GO:0006874
GO:0006941
GO:0010649
GO:0010880
GO:0010881
GO:0014701
GO:0016529
GO:0023052
GO:0030018
GO:0033017
GO:0033018
GO:0034704
GO:0042803
GO:0043226
GO:0043267
GO:0046872
GO:0048306
GO:0051208
GO:0051258
GO:0060048
GO:0060306
GO:0060315
GO:0065003
GO:0071313
GO:0086029
GO:0140313
GO:0140314
GO:1901017
HMNXSV003021838
HMNXSV003028825
HMNXSV003045384
Hs.46296.0.S1_3p_a_at
Hs.46296.0.S1_3p_x_at
ILMN_1722329
PH_hs_0003724
PH_hs_0028885
TC01003020.hg
g4557408_3p_s_at
Participates
as a repeated unit of
CASQ2 polymer [sarcoplasmic reticulum lumen] (Homo sapiens)
Inferred To
Casq2 [sarcoplasmic reticulum membrane]
(Mus musculus)
Casq2 [sarcoplasmic reticulum membrane]
(Rattus norvegicus)
CASQ2 [sarcoplasmic reticulum membrane]
(Bos taurus)
CASQ2 [sarcoplasmic reticulum membrane]
(Canis familiaris)
CASQ2 [sarcoplasmic reticulum membrane]
(Sus scrofa)
Cross References
ENSEMBL
ENST00000261448
,
ENSP00000261448
OpenTargets
ENSG00000118729
HPA
ENSG00000118729-CASQ2
PRO
O14958
Pharos - Targets
O14958
GlyGen
O14958
Orphanet
CASQ2
HMDB Protein
HMDBP07556
PDB
2VAF
,
6OWW
,
6OWV
,
7F05
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13895 BYSL
2
BYSL [nucleoplasm]
(R-HSA-6791526)
BYSL [cytosol]
(R-HSA-6791518)
0.556
3
UniProt:Q14137 BOP1
1
BOP1 [nucleoplasm]
(R-HSA-6791206)
0.527
2
UniProt:P62736 ACTA2
1
ACTA2 [cytosol]
(R-HSA-445792)
0.527
2
UniProt:Q14999 CUL7
1
CUL7 [cytosol]
(R-HSA-535534)
0.527
2
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