Reactome | FN1 dimer [extracellular region]

FN1 dimer [extracellular region]

Stable Identifier

R-HSA-266103

Type

Complex

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Fibronectin dimer

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by Receptor Tyrosine Kinases (Homo sapiens)
  - Signaling by MET (Homo sapiens)
    - MET promotes cell motility (Homo sapiens)
      - MET activates PTK2 signaling (Homo sapiens)
        
        PTK2 binds activated MET (Homo sapiens)
        
        Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens)
        
        Collagen, laminin, fibronectin [extracellular region] (Homo sapiens)
        
        Fibronectin matrix [extracellular region] (Homo sapiens)
        
        FN1 dimer [extracellular region] (Homo sapiens)

Participants

components

2 x FN1(32-2386) [extracellular region] (Homo sapiens)

Participant Of

input

Integrin alpha5beta1 binds FN1 dimer

repeatedUnit

Fibronectin matrix [extracellular region]

output

FN1 dimerizes

hasComponent

Integrin alpha5beta1:FN1 dimer [plasma membrane]

Inferred To

FN1 dimer [extracellular region] (Bos taurus)

FN1 dimer [extracellular region] (Canis familiaris)

FN1 dimer [extracellular region] (Danio rerio)

FN1 dimer [extracellular region] (Drosophila melanogaster)

FN1 dimer [extracellular region] (Gallus gallus)

FN1 dimer [extracellular region] (Mus musculus)

FN1 dimer [extracellular region] (Rattus norvegicus)

FN1 dimer [extracellular region] (Sus scrofa)

FN1 dimer [extracellular region] (Taeniopygia guttata)

FN1 dimer [extracellular region] (Xenopus tropicalis)

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