Loading of acetylcholine in synaptic vesicles

Stable Identifier
R-HSA-264615
Type
Reaction
Species
Homo sapiens
Compartment
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Acetylcholine is actively transported from the cytosol to the lumen of the synaptic vesicle by vesicular acetylcholine transporter. Two protons are exchanged for 1 molecule of acetylcholine. The vesicular acetylcholine transporter is located in the membrane of the synaptic vesicle.

Literature References
PubMed ID Title Journal Year
8071310 Functional identification of a vesicular acetylcholine transporter and its expression from a "cholinergic" gene locus

Eiden, LE, Diebler, MF, Varoqui, H, Weihe, E, Usdin, TB, Erickson, JD, Modi, W, Rand, J, Bonner, TI, Schäfer, MK

J Biol Chem 1994
Participants
Participates
Catalyst Activity

acetylcholine transmembrane transporter activity of SLC18A3 [clathrin-sculpted acetylcholine transport vesicle membrane]

Orthologous Events
Authored
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