ACVR2A/B (ActRIIA/B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin

Stable Identifier
R-HSA-2470508
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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As inferred from mouse, upon binding Activin AB (INHBA:INHBB) or Activin B (INHBB:INHBB), the type II component of the activin receptor (ACVR2A or ACVR2B) phosphorylates the type I component ACVR1C (ALK7) at multiple serine and threonine residues within the GS domain.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of Activin AB,B:ACVR2A,B:ACVR1C [plasma membrane]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created