atRAL is reduced to atROL

Stable Identifier
R-HSA-2465940
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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All-trans-retinal (atRAL) can diffuse across membranes to the cytosol and is reduced to all-trans-retinol (atROL) by the action of a short-chain dehydrogenase/reductase 3 using NADP+/NADPH as cofactor (Haeseleer et al. 1998).

Literature References
PubMed ID Title Journal Year
9705317 Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal

Haeseleer, F, Huang, J, Lebioda, L, Saari, JC, Palczewski, K

J. Biol. Chem. 1998
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
NADP-retinol dehydrogenase activity of DHRS3 [photoreceptor outer segment membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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