IRS2 binds the NPEY-juxtamembrane motif of phosphorylated IGF1R (He et al. 1996, Kim et al. 1998). IRS2 is cytosolic while IRS1 and IRS4 are located in the plasma membrane.
Feldman, EL, Cheng, HL, Margolis, B, Kim, B
Zhu, Y, O'Neill, TJ, Gustafson, TA, Craparo, A, He, W, Pierce, JH, Wang, LM
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