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SREBP1A,2:NF-Y:SP1:PMVK gene [nucleoplasm]
Stable Identifier
R-HSA-2426139
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SREBF1A,2:NF-Y:SP1:PMVK gene
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
Activation of gene expression by SREBF (SREBP) (Homo sapiens)
Expression of Phosphomevalonate Kinase (PMVK) (Homo sapiens)
SREBP1A,2:NF-Y:SP1:PMVK gene [nucleoplasm] (Homo sapiens)
SREBP1A,2 binds the PMVK promoter (Homo sapiens)
SREBP1A,2:NF-Y:SP1:PMVK gene [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
18654640
Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes
Szekely, AM
,
Weissman, SM
,
Reed, BD
,
Snyder, M
,
Charos, AE
PLoS Genet
2008
Participants
components
NF-Y [nucleoplasm]
(Homo sapiens)
PMVK gene [nucleoplasm]
(Homo sapiens)
SP1 [nucleoplasm]
(Homo sapiens)
SREBP1A,2 dimer [nucleoplasm]
(Homo sapiens)
Participates
as an output of
SREBP1A,2 binds the PMVK promoter (Homo sapiens)
This entity regulates
Positively
Expression of Phosphomevalonate Kinase (PMVK)
(Homo sapiens)
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