SeHCys and Ser are dehydrated into SeCysta by CBS

Stable Identifier
R-HSA-2408559
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SeHCys and Ser are dehydrated into SeCysta by CBS
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Cystathionine beta-synthase (CBS) is involved in the dehydration of selenohomocysteine (SeHCys) and serine that produces selenocystathionine (SeCysta). This reaction is inferred from the event in rat involving the protein cystathionine beta-synthase (Cbs) (Esaki et al. 1981).
Literature References
PubMed ID Title Journal Year
6456763 Enzymatic synthesis of selenocysteine in rat liver

Esaki, N, Nakamura, T, Tanaka, H, Suzuki, T, Morino, Y, Soda, K

Biochemistry 1981
Participants
Input
Output
Participates
as an event of
Catalyst Activity

selenocystathionine beta-synthase activity of PXLP-K119-CBS tetramer [cytosol]

Physical Entity
PXLP-K119-CBS tetramer [cytosol] (Homo sapiens)
Activity
selenocystathionine beta-synthase activity (GO:0098605)
Inferred From
SeHCys and Ser are dehydrated into SeCysta by Cbs (Rattus norvegicus)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2012-07-17)
Cite Us!