SeHCys and Ser are dehydrated into SeCysta by CBS

Stable Identifier
R-HSA-2408559
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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SeHCys and Ser are dehydrated into SeCysta by CBS
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Cystathionine beta-synthase (CBS) is involved in the dehydration of selenohomocysteine (SeHCys) and serine that produces selenocystathionine (SeCysta). This reaction is inferred from the event in rat involving the protein cystathionine beta-synthase (Cbs) (Esaki et al. 1981).
Literature References
PubMed ID Title Journal Year
6456763 Enzymatic synthesis of selenocysteine in rat liver

Esaki, N, Nakamura, T, Morino, Y, Soda, K, Tanaka, H, Suzuki, T

Biochemistry 1981
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Catalyst Activity

selenocystathionine beta-synthase activity of PXLP-K119-CBS tetramer [cytosol]

Physical Entity
PXLP-K119-CBS tetramer [cytosol] (Homo sapiens)
Activity
selenocystathionine beta-synthase activity (GO:0098605)
Inferred From
SeHCys and Ser are dehydrated into SeCysta by Cbs (Rattus norvegicus)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2012-07-17)
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