IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1

Stable Identifier
R-HSA-2404195
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1
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SHC binds the NPEY-juxtamembrane motif of the phosphorylated insulin-like growth factor receptor (IGF1R) (Giorgetti et al. 1994, Tartare-Deckert et al. 1995).
Literature References
PubMed ID Title Journal Year
7559507 Evidence for a differential interaction of SHC and the insulin receptor substrate-1 (IRS-1) with the insulin-like growth factor-I (IGF-I) receptor in the yeast two-hybrid system

Tartare-Deckert, S, Sawka-Verhelle, D, Murdaca, J, Van Obberghen, E

J. Biol. Chem. 1995
8033892 Involvement of Src-homology/collagen (SHC) proteins in signaling through the insulin receptor and the insulin-like-growth-factor-I-receptor

Giorgetti, S, Pelicci, PG, Pelicci, G, Van Obberghen, E

Eur. J. Biochem. 1994
Participants
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Orthologous Events
IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Bos taurus)
IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Canis familiaris)
IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Gallus gallus)
IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Mus musculus)
IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Rattus norvegicus)
IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Sus scrofa)
Authored
May, B  (2012-07-08)
Reviewed
Holzenberger, M  (2012-11-10)
Created
May, B  (2012-07-16)
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