VTN binds collagens II, III and V

Stable Identifier
R-HSA-2396370
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Vitronectin binds collagens II, III and V
ReviewStatus
5/5
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VTN binds collagens II, III and V
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Vitronectin (VTN) is a major plasma glycoprotein of 75 kDa, circulating at approximately 0.2 mg/ml in humans. It interacts with collagen types I, II, III, IV, V, and VI (Gebb et al. 1986). Deglycosylation enhances VTN binding to collagen and is associated with VTN multimerization (Uchibori-Iwaki et al. 2000, Sano et al. 2007).
Literature References
PubMed ID Title Journal Year
2430969 Interaction of vitronectin with collagen

Hayman, EG, Gebb, C, Ruoslahti, E, Engvall, E

J. Biol. Chem. 1986
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Orthologous Events
VTN binds collagens II, III and V (Bos taurus)
VTN binds collagens II, III and V (Canis familiaris)
VTN binds collagens II, III and V (Gallus gallus)
VTN binds collagens II, III and V (Mus musculus)
VTN binds collagens II, III and V (Rattus norvegicus)
VTN binds collagens II, III and V (Sus scrofa)
VTN binds collagens II, III and V (Xenopus tropicalis)
Authored
Jupe, S  (2013-01-10)
Reviewed
Ricard-Blum, S  (2013-05-22)
Venkatesan, N  (2013-05-21)
Created
Jupe, S  (2012-07-09)
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