MARCO:ligand is endocytosed

Stable Identifier
Reaction [omitted]
Homo sapiens
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The MARCO:ligand complex is endocytosed (Arredouani et al. 2005, Thelen et al. 2010). In cases where the ligand is part of a bacterial cell the entire cell is phagocytosed.

Literature References
PubMed ID Title Journal Year
20810988 The class A scavenger receptor, macrophage receptor with collagenous structure, is the major phagocytic receptor for Clostridium sordellii expressed by human decidual macrophages

Thelen, T, Hao, Y, Medeiros, AI, Curtis, JL, Serezani, CH, Kobzik, L, Harris, LH, Aronoff, DM

J Immunol 2010
16237101 MARCO is the major binding receptor for unopsonized particles and bacteria on human alveolar macrophages

Arredouani, MS, Palecanda, A, Koziel, H, Huang, YC, Imrich, A, Sulahian, TH, Ning, YY, Yang, Z, Pikkarainen, T, Sankala, M, Vargas, SO, Takeya, M, Tryggvason, K, Kobzik, L

J Immunol 2005
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Orthologous Events