MARCO:ligand is endocytosed

Stable Identifier
R-HSA-2247510
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
plasma membrane, endocytic vesicle membrane
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MARCO:ligand is endocytosed
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The MARCO:ligand complex is endocytosed (Arredouani et al. 2005, Thelen et al. 2010). In cases where the ligand is part of a bacterial cell the entire cell is phagocytosed.

Literature References
PubMed ID Title Journal Year
16237101 MARCO is the major binding receptor for unopsonized particles and bacteria on human alveolar macrophages

Takeya, M, Arredouani, MS, Sankala, M, Sulahian, TH, Pikkarainen, T, Imrich, A, Koziel, H, Kobzik, L, Huang, YC, Yang, Z, Palecanda, A, Tryggvason, K, Vargas, SO, Ning, YY

J Immunol 2005
20810988 The class A scavenger receptor, macrophage receptor with collagenous structure, is the major phagocytic receptor for Clostridium sordellii expressed by human decidual macrophages

Medeiros, AI, Aronoff, DM, Kobzik, L, Serezani, CH, Harris, LH, Curtis, JL, Hao, Y, Thelen, T

J Immunol 2010
Participants
Input
Output
Participates
as an event of
Orthologous Events
MARCO:ligand is endocytosed (Canis familiaris)
MARCO:ligand is endocytosed (Mus musculus)
MARCO:ligand is endocytosed (Rattus norvegicus)
Authored
Neyen, C  (2013-03-22)
May, B  (2013-01-26)
Reviewed
Neyen, C  (2013-03-22)
Created
May, B  (2012-05-12)
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