PDPK1 binds PIP2

Stable Identifier
R-HSA-2219524
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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PDPK1 (PDK1) possesses low affinity for PIP2, so small amounts of PDPK1 are always present at the membrane, in the absence of PI3K activity (Currie et al. 1999).

Literature References
PubMed ID Title Journal Year
9895304 Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

Currie, RA, Walker, KS, Gray, A, Deak, M, Casamayor, A, Downes, CP, Cohen, P, Alessi, DR, Lucocq, J

Biochem J 1999
Participants
Participant Of
Orthologous Events
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Created