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STAB2(1136-2551) [plasma membrane]
Stable Identifier
R-HSA-2160853
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
STAB2, Stabilin-2, STAB2_HUMAN, HARE, Hyaluronan receptor for endocytosis, 190 kDa form stabilin-2
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Hyaluronan metabolism (Homo sapiens)
Hyaluronan uptake and degradation (Homo sapiens)
HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ (Homo sapiens)
HA:HAR:HYAL2 [plasma membrane] (Homo sapiens)
HARs [plasma membrane] (Homo sapiens)
STAB2(1136-2551) [plasma membrane] (Homo sapiens)
HA:HAR:HYAL2:SLC9A1:pCHP:Ca2+ [plasma membrane] (Homo sapiens)
HA:HAR:HYAL2 [plasma membrane] (Homo sapiens)
HARs [plasma membrane] (Homo sapiens)
STAB2(1136-2551) [plasma membrane] (Homo sapiens)
Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments (Homo sapiens)
HA:HAR:HYAL2:SLC9A1:pCHP:Ca2+ [plasma membrane] (Homo sapiens)
HA:HAR:HYAL2 [plasma membrane] (Homo sapiens)
HARs [plasma membrane] (Homo sapiens)
STAB2(1136-2551) [plasma membrane] (Homo sapiens)
Receptor-mediated uptake of HA (Homo sapiens)
HA:HAR:HYAL2 [plasma membrane] (Homo sapiens)
HARs [plasma membrane] (Homo sapiens)
STAB2(1136-2551) [plasma membrane] (Homo sapiens)
HARs [plasma membrane] (Homo sapiens)
STAB2(1136-2551) [plasma membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)
Scavenging by Class H Receptors (Homo sapiens)
STAB2 (FEEL-2) binds ligands (Homo sapiens)
STAB2(1136-2551) [plasma membrane] (Homo sapiens)
STAB2:Ligand [plasma membrane] (Homo sapiens)
STAB2(1136-2551) [plasma membrane] (Homo sapiens)
STAB2:ligand is endocytosed (Homo sapiens)
STAB2:Ligand [plasma membrane] (Homo sapiens)
STAB2(1136-2551) [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WWQ8 STAB2
Gene Names
STAB2, FEEL2, FELL, FEX2, HARE
Chain
signal peptide:1-19, chain:20-2551, chain:1136-2551
Reference Genes
BioGPS Gene:55576 STAB2
COSMIC (genes):STAB2 STAB2
CTD Gene:55576 STAB2
dbSNP Gene:55576 STAB2
ENSEMBL:ENSG00000136011 STAB2
ENSEMBL_homo_sapiens_GENE:ENSG00000136011.15 STAB2
HGNC:18629 STAB2
KEGG Gene (Homo sapiens):55576 STAB2
Monarch:55576 STAB2
NCBI Gene:55576 STAB2
OMIM:608561 STAB2
UCSC:Q8WWQ8 STAB2
Reference Transcript
RefSeq:NM_017564.9 STAB2
Other Identifiers
11756904_a_at
16755988
220114_PM_s_at
220114_s_at
3429162
3429163
3429167
3429170
3429173
3429174
3429175
3429177
3429178
3429180
3429181
3429182
3429183
3429184
3429185
3429187
3429188
3429189
3429190
3429191
3429193
3429194
3429195
3429198
3429199
3429201
3429202
3429203
3429204
3429205
3429207
3429208
3429210
3429211
3429212
3429213
3429214
3429215
3429216
3429217
3429218
3429220
3429222
3429226
3429229
3429230
3429235
3429236
3429239
3429240
3429242
3429243
3429244
3429245
3429246
3429247
3429249
3429250
3429251
3429252
3429253
3429254
3429255
3429258
3429259
3429260
3429261
3429262
3429265
3429266
3429267
3429269
3429270
3429271
3429272
3429273
3429276
3429278
3429279
55576
62964_at
7958056
A_14_P110846
A_14_P123872
A_14_P132453
A_23_P162607
GE56577
GO:0001525
GO:0003824
GO:0005041
GO:0005044
GO:0005509
GO:0005515
GO:0005540
GO:0005737
GO:0005829
GO:0005886
GO:0006897
GO:0006898
GO:0007155
GO:0009897
GO:0015035
GO:0016020
GO:0016192
GO:0016491
GO:0030169
GO:0030214
GO:0030666
GO:0031410
GO:0038024
GO:0042742
GO:0043226
GO:0048856
GO:0050830
GO:0098542
GO:0140096
GO:1901135
HMNXSV003051564
HMNXSV003051981
ILMN_1677497
PH_hs_0024739
TC12000799.hg
g12583704_3p_a_at
Participates
as an input of
STAB2 (FEEL-2) binds ligands (Homo sapiens)
as a component of
STAB2:Ligand [plasma membrane] (Homo sapiens)
as a member of
HARs [plasma membrane] (Homo sapiens)
Other forms of this molecule
STAB2(1136-2551) [endocytic vesicle membrane]
Inferred To
stab2 [plasma membrane]
(Xenopus tropicalis)
STAB2(1136-2551) [plasma membrane]
(Gallus gallus)
Stab2 [plasma membrane]
(Mus musculus)
STAB2 [plasma membrane]
(Bos taurus)
STAB2 [plasma membrane]
(Canis familiaris)
STAB2 [plasma membrane]
(Sus scrofa)
sibE [plasma membrane]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_060034.9
OpenTargets
ENSG00000136011
HPA
ENSG00000136011-STAB2
GeneCards
Q8WWQ8
Ensembl
ENSG00000136011
,
ENSP00000373539
,
ENST00000388887
PRO
Q8WWQ8
Pharos - Targets
Q8WWQ8
HMDB Protein
HMDBP10895
PDB
5N86
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P20065
2
Tmsb4x [extracellular region]
(R-MMU-349753)
Tmsb4x [platelet alpha granule lumen]
(R-MMU-349758)
0.591
3
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