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HLA class II histocompatibility antigen, DR beta 5 chain [clathrin-coated endocytic vesicle membrane]
Stable Identifier
R-HSA-2130548
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
clathrin-coated endocytic vesicle membrane
Synonyms
HLA-DRB5, DRB5_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Internalization of MHC II:Ii clathrin coated vesicle (Homo sapiens)
Clathrin coated MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
MHC class II alpha/beta dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
HLA II beta chain [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 5 chain [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Uncoating of clathrin-coated vesicles and fusion with endosomes (Homo sapiens)
Clathrin coated MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
MHC class II alpha/beta dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
HLA II beta chain [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
HLA class II histocompatibility antigen, DR beta 5 chain [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q30154 HLA-DRB5
Gene Names
HLA-DRB5
Chain
signal peptide:1-29, chain:30-266
Reference Genes
BioGPS Gene:3127 HLA-DRB5
COSMIC (genes):HLA-DRB5 HLA-DRB5
CTD Gene:3127 HLA-DRB5
dbSNP Gene:3127 HLA-DRB5
ENSEMBL:ENSG00000198502 HLA-DRB5
ENSEMBL_homo_sapiens_GENE:ENSG00000198502.6 HLA-DRB5
HGNC:4953 HLA-DRB5
KEGG Gene (Homo sapiens):3127 HLA-DRB5
Monarch:3127 HLA-DRB5
NCBI Gene:3127 HLA-DRB5
OMIM:604776 HLA-DRB5
UCSC:Q30154 HLA-DRB5
Reference Transcript
RefSeq:NM_002125.3 HLA-DRB5
Other Identifiers
11720657_x_at
17017885
215193_PM_x_at
215193_x_at
2950023
2950025
2950033
2950046
2950057
2950060
2950067
3127
4048242
4048243
4048245
4048247
4048248
4048249
4048251
4048252
4048253
4048256
4048257
4048258
4048272
4048288
8125436
A_23_P45099
GE88565
GO:0000139
GO:0002250
GO:0002376
GO:0002503
GO:0002504
GO:0005576
GO:0005615
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006955
GO:0007155
GO:0010008
GO:0012507
GO:0016020
GO:0019882
GO:0019886
GO:0023026
GO:0030658
GO:0030666
GO:0030669
GO:0031410
GO:0031902
GO:0032588
GO:0042605
GO:0042613
GO:0043226
GO:0050778
GO:0050870
GO:0065003
GO:0070062
GO:0098553
HMNXSV003053454
Hs.279930.1.S1_3p_x_at
ILMN_1697499
TC06004122.hg
TC6_dbb_hap3000180.hg
Participates
as a member of
HLA II beta chain [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Other forms of this molecule
HLA class II histocompatibility antigen, DR beta 5 chain [lumenal side of endoplasmic reticulum membrane]
HLA class II histocompatibility antigen, DR beta 5 chain [ER to Golgi transport vesicle membrane]
HLA class II histocompatibility antigen, DR beta 5 chain [Golgi membrane]
HLA class II histocompatibility antigen, DR beta 5 chain [trans-Golgi network membrane]
HLA class II histocompatibility antigen, DR beta 5 chain [transport vesicle membrane]
HLA class II histocompatibility antigen, DR beta 5 chain [endocytic vesicle membrane]
HLA class II histocompatibility antigen, DR beta 5 chain [lysosomal membrane]
HLA class II histocompatibility antigen, DR beta 5 chain [plasma membrane]
Inferred To
zmp:0000001138 [clathrin-coated endocytic vesicle membrane]
(Danio rerio)
HLA class II histocompatibility antigen, DR beta 4 chain [clathrin-coated endocytic vesicle membrane]
(Bos taurus)
HLA class II histocompatibility antigen, DR beta 4 chain [clathrin-coated endocytic vesicle membrane]
(Gallus gallus)
HLA class II histocompatibility antigen, DR beta 4 chain [clathrin-coated endocytic vesicle membrane]
(Sus scrofa)
RT1-Db1 [clathrin-coated endocytic vesicle membrane]
(Rattus norvegicus)
LOC100153139 [clathrin-coated endocytic vesicle membrane]
(Sus scrofa)
H2-Eb2 [clathrin-coated endocytic vesicle membrane]
(Mus musculus)
SLA-DRB1 [clathrin-coated endocytic vesicle membrane]
(Sus scrofa)
b2m [clathrin-coated endocytic vesicle membrane]
(Danio rerio)
mhc2-dab [clathrin-coated endocytic vesicle membrane]
(Xenopus tropicalis)
BLB2 [clathrin-coated endocytic vesicle membrane]
(Gallus gallus)
BOLA-DRB3 [clathrin-coated endocytic vesicle membrane]
(Bos taurus)
H2-Eb1 [clathrin-coated endocytic vesicle membrane]
(Mus musculus)
BOLA-DRB2 [clathrin-coated endocytic vesicle membrane]
(Bos taurus)
BLB1 [clathrin-coated endocytic vesicle membrane]
(Gallus gallus)
Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [clathrin-coated endocytic vesicle membrane]
(Bos taurus)
Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [clathrin-coated endocytic vesicle membrane]
(Danio rerio)
Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [clathrin-coated endocytic vesicle membrane]
(Gallus gallus)
Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [clathrin-coated endocytic vesicle membrane]
(Mus musculus)
Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [clathrin-coated endocytic vesicle membrane]
(Rattus norvegicus)
Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [clathrin-coated endocytic vesicle membrane]
(Sus scrofa)
RT1-Db2 [clathrin-coated endocytic vesicle membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_002116.2
OpenTargets
ENSG00000198502
HPA
ENSG00000198502-HLA-DRB5
GeneCards
Q30154
Ensembl
ENSP00000364114
,
ENST00000374975
,
ENSG00000198502
PRO
Q30154
Pharos - Targets
Q30154
PDB
1HQR
,
1H15
,
1FV1
,
1ZGL
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14757 CHEK1
3
CHEK1 [cytosol]
(R-HSA-205285)
CHEK1 [nucleoplasm]
(R-HSA-113826)
p-S317,S345-CHEK1 [nucleoplasm]
(R-HSA-113838)
0.564
2
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