DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm]

Stable Identifier
R-HSA-212288
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
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General

The Polycomb Repressor Complex 2 (PRC2) is able to interact with and recruit DNMT1, DNMT3a, and DNMT3b, all of which transfer a methyl group from S-adenosylmethionine to the 5 position of the cytosine ring.EZH2 is required for DNA methylation at PRC2 targets.

Participants
components
Participates
as an input of
as an output of
Inferred To
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Bos taurus)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Canis familiaris)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Danio rerio)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Gallus gallus)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Mus musculus)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Rattus norvegicus)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Sus scrofa)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Xenopus tropicalis)
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