Interaction of PAK-2p34 with RGH10/ PS-GAP results in accumulation of PAK-2p34 in the perinuclear region

Stable Identifier
R-HSA-211731
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Interaction of PAK-2p34 with RGH10/ PS-GAP results in accumulation of PAK-2p34 in the perinuclear region
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Following caspase mediated cleavage, PAK-2p34 translocates to the nucleus (Jakobi et al., 2003). The interaction with PS-GAP changes the localization of PAK-2p34 from the nucleus to the perinuclear region (Koeppel et al.,2004).
Literature References
PubMed ID Title Journal Year
15471851 Identification and characterization of PS-GAP as a novel regulator of caspase-activated PAK-2

Jakobi, R, Koeppel, MA, McCarthy, CC, Moertl, E

J Biol Chem 2004
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Interaction of PAK-2p34 with PS-GAP results in accumulation of PAK-2p34 in the perinuclear region (Mus musculus)
Authored
Jakobi, R  (2008-02-05)
Reviewed
Chang, E  (2008-05-21)
Created
Matthews, L  (2008-02-08)
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