Reactome | FOXA3 [nucleoplasm]

FOXA3 [nucleoplasm]

Stable Identifier

R-HSA-211484

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Forkhead box protein A3, Hepatocyte nuclear factor 3-gamma

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P55318 FOXA3

Gene Names

FOXA3, HNF3G, TCF3G

Chain

chain:1-350

Reference Genes

BioGPS Gene:3171 FOXA3

COSMIC (genes):FOXA3 FOXA3

CTD Gene:3171 FOXA3

dbSNP Gene:3171 FOXA3

ENSEMBL:ENSG00000170608 FOXA3

HGNC:5023 FOXA3

KEGG:hsa:3171 FOXA3

Monarch:3171 FOXA3

NCBI Gene:3171 FOXA3

OMIM:602295 FOXA3

UCSC:P55318 FOXA3

Reference Transcript

RefSeq:NM_004497.2 FOXA3

Other Identifiers

11727662_at

16863370

228463_PM_at

228463_at

3171

3836535

3836536

3836537

3836539

3836540

3836541

45381_at

45382_g_at

52543_at

8029754

A_14_P101521

A_23_P142174

A_23_P208737

GE81402

GO:0000785

GO:0000976

GO:0000978

GO:0000981

GO:0001678

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005856

GO:0006325

GO:0006351

GO:0006355

GO:0006357

GO:0006366

GO:0007283

GO:0008134

GO:0009267

GO:0009653

GO:0015629

GO:0019904

GO:0022414

GO:0030154

GO:0043226

GO:0043565

GO:0045893

GO:0045944

GO:0061484

GO:0140110

GO:1990837

HMNXSV003042384

Hs.36137.0.S2_3p_at

ILMN_1792733

PH_hs_0002892

TC19000656.hg

Participates

as an output of

HNF1A-dependent synthesis of FOXA3 (Homo sapiens)

Cross References

ENSEMBL

ENSG00000170608, ENST00000302177, ENSP00000304004

OpenTargets

ENSG00000170608

GeneCards

FOXA3

HPA

ENSG00000170608-FOXA3

PRO

P55318

Pharos - Targets

P55318

PDB

1VTN

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P22607 FGFR3	20	FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 805fs*141 [plasma membrane] (R-HSA-1614387) p-6Y-FGFR3 A391E [plasma membrane] (R-HSA-2065835) p-6Y-FGFR3 K650T [plasma membrane] (R-HSA-2032966) p-6Y-FGFR3 G382D [plasma membrane] (R-HSA-2032950) p-6Y-FGFR3 G380R [plasma membrane] (R-HSA-2032946) p-6Y-FGFR3 K650M [plasma membrane] (R-HSA-2032959)	0.556	3
UniProt:P28329-3 P283293			0.556	3
UniProt:Q16842 ST3GAL2	1	ST3GAL2 [Golgi membrane] (R-HSA-981482)	0.527	2
UniProt:P31146 CORO1A	1	CORO1A [cytosol] (R-HSA-9636432)	0.527	2
UniProt:Q5VWX1 KHDRBS2	2	KHDRBS2 [nucleoplasm] (R-HSA-8849028) p-Y-KHDRBS2 [nucleoplasm] (R-HSA-8849031)	0.527	2

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