L-Glutamate loading of synaptic vesicle

Stable Identifier
R-HSA-210444
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Nascent synaptic vesicles are loaded with glutamate by VGLUT1 to form glutamate containing synaptic vesicles. This process occurs while the synaptic vesicle is in the cytosol.

Literature References
PubMed ID Title Journal Year
18215623 Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3

Seal, RP, Kandler, K, Glowatzki, E, Edwards, RH, Yoo, J, Noebels, JL, Lustig, LR, Grant, L, Clause, A, Yi, E, Akil, O, Weber, CM

Neuron 2008
11001057 Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons

Jahn, R, Rosenmund, C, Takamori, S, Rhee, JS

Nature 2000
Participants
Participates
Catalyst Activity

L-glutamate transmembrane transporter activity of Empty Glutamate Synaptic Vesicle [cytosol]

Orthologous Events
Authored
Reviewed
Created
Cite Us!