L-Glutamate loading of synaptic vesicle

Stable Identifier
R-HSA-210444
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Nascent synaptic vesicles are loaded with glutamate by VGLUT1 to form glutamate containing synaptic vesicles. This process occurs while the synaptic vesicle is in the cytosol.
Literature References
PubMed ID Title Journal Year
18215623 Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3

Seal, RP, Kandler, K, Glowatzki, E, Edwards, RH, Yoo, J, Noebels, JL, Lustig, LR, Grant, L, Clause, A, Yi, E, Akil, O, Weber, CM

Neuron 2008
11001057 Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons

Jahn, R, Rosenmund, C, Takamori, S, Rhee, JS

Nature 2000
Participants
Participates
Catalyst Activity

L-glutamate transmembrane transporter activity of Empty Glutamate Synaptic Vesicle [cytosol]

Orthologous Events
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