L-Glutamate loading of synaptic vesicle

Stable Identifier
R-HSA-210444
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Nascent synaptic vesicles are loaded with glutamate by VGLUT1 to form glutamate containing synaptic vesicles. This process occurs while the synaptic vesicle is in the cytosol.

Literature References
PubMed ID Title Journal Year
11001057 Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons

Takamori, S, Rhee, JS, Rosenmund, C, Jahn, R

Nature 2000
18215623 Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3

Seal, RP, Akil, O, Yi, E, Weber, CM, Grant, L, Yoo, J, Clause, A, Kandler, K, Noebels, JL, Glowatzki, E, Lustig, LR, Edwards, RH

Neuron 2008
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
L-glutamate transmembrane transporter activity of Empty Glutamate Synaptic Vesicle [cytosol]
Physical Entity
Activity
Orthologous Events
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Created