Reactome | DBH(40-617) [secretory granule lumen]

DBH(40-617) [secretory granule lumen]

Stable Identifier

R-HSA-209790

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

secretory granule lumen

Synonyms

Dopamine beta-monooxygenase, DBH

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P09172 DBH

Gene Names

DBH

Chain

chain:1-617, chain:40-617

Reference Genes

BioGPS Gene:1621 DBH

COSMIC (genes):DBH DBH

CTD Gene:1621 DBH

dbSNP Gene:1621 DBH

ENSEMBL:ENSG00000123454 DBH

HGNC:2689 DBH

KEGG:hsa:1621 DBH

Monarch:1621 DBH

NCBI Gene:1621 DBH

OMIM:609312 DBH

UCSC:P09172 DBH

Reference Transcript

RefSeq:NM_000787.3 DBH

Other Identifiers

11744309_at

1621

17090864

206450_PM_at

206450_at

3192866

3192867

3192871

3192872

3192873

3192874

3192875

3192876

3192877

3192878

3192879

3192881

3192883

3192885

3192886

3192887

32943_at

8159096

A_23_P112296

GE80954

GO:0001974

GO:0001975

GO:0002376

GO:0002443

GO:0003013

GO:0003824

GO:0004497

GO:0004500

GO:0005507

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0005783

GO:0006589

GO:0007268

GO:0007613

GO:0007626

GO:0008306

GO:0008542

GO:0016020

GO:0016491

GO:0016715

GO:0022414

GO:0023052

GO:0030658

GO:0030667

GO:0031410

GO:0031418

GO:0034451

GO:0034466

GO:0034774

GO:0042309

GO:0042310

GO:0042420

GO:0042421

GO:0042423

GO:0042584

GO:0042593

GO:0042596

GO:0042711

GO:0043226

GO:0043231

GO:0045202

GO:0045907

GO:0046872

GO:0048149

GO:0048265

GO:0048870

GO:0050877

GO:0050900

GO:0120162

GO:1904705

GO:1905562

GO:2001236

HMNXSV003003638

ILMN_1746220

TC09000778.hg

X13255_at

g4503260_3p_at

Participates

as a component of

DBH tetramer [secretory granule lumen] (Homo sapiens)

Inferred To

DBH(40-617) [secretory granule lumen] (Drosophila melanogaster)

DBH(40-617) [secretory granule lumen] (Gallus gallus)

DBH(40-617) [secretory granule lumen] (Mus musculus)

DBH(40-617) [secretory granule lumen] (Rattus norvegicus)

DBH [secretory granule lumen] (Bos taurus)

DBH [secretory granule lumen] (Canis familiaris)

DBH [secretory granule lumen] (Sus scrofa)

dbh [secretory granule lumen] (Danio rerio)

dbh [secretory granule lumen] (Xenopus tropicalis)

Cross References

Guide to Pharmacology - Targets

2486

ENSEMBL

ENST00000393056, ENSP00000376776

OpenTargets

ENSG00000123454

ZINC - Substances

DOPO_HUMAN

ZINC target

P09172

PRO

P09172

PDB

4ZEL

IntEnz

1.14.17.1

HPA

ENSG00000123454-DBH

Pharos - Targets

P09172

Orphanet

DBH

ZINC - Predictions - Purchasable

DOPO_HUMAN

HMDB Protein

HMDBP00253

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:Q14693 LPIN1	3	LPIN1 [endoplasmic reticulum membrane] (R-HSA-549157) LPIN1 [nuclear envelope] (R-HSA-4419927) p-S106-LPIN1 [nucleoplasm] (R-HSA-4419936)	0.556	3
UniProt:P61978 HNRNPK	2	HNRNPK [nucleoplasm] (R-HSA-71945) polySUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.556	3
UniProt:Q04656 ATP7A	3	ATP7A [phagocytic vesicle membrane] (R-HSA-6803546) ATP7A [trans-Golgi network membrane] (R-HSA-3697896) ATP7A [plasma membrane] (R-HSA-936841)	0.499	2