Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
NADP+ [endoplasmic reticulum lumen]
Stable Identifier
R-ALL-113564
Type
Chemical Compound [SimpleEntity]
Compartment
endoplasmic reticulum lumen
Synonyms
NADP, NADP(+), Nicotinamide adenine dinucleotide phosphate, beta-Nicotinamide adenine dinucleotide phosphate, TPN, Triphosphopyridine nucleotide
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Cytochrome P450 - arranged by substrate type (Bos taurus)
Eicosanoids (Bos taurus)
CYP4F8 19-hydroxylates PGH2 (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Fatty acids (Bos taurus)
CYP2J2 oxidises ARA (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP4A11 12-hydroxylates DDCX (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Bos taurus)
CYP2S1 4-hydroxylates atRA (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP2U1 19-hydroxylates ARA (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP3A43 6b-hydroxylates TEST (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP4F11 16-hydroxylates 3OH-PALM (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Vitamins (Bos taurus)
CYP26A1,B1 4-hydroxylate atRA (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Bos taurus)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Bos taurus)
N-atom dealkylation of caffeine (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
N-hydroxylation of 4-aminobiphenyl (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP2C19 5-hydroxylates omeprazole (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP2D6 4-hydroxylates debrisoquine (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Bos taurus)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP2F1 dehydrogenates 3-methylindole (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP3A4 can N-demethylate loperamide (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP3A4,5 oxidise AFB1 to AFXBO (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
CYP3A7 can 6beta-hydroxylate testosterone (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A13 (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A6 (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
FMO oxidises nucleophiles (Bos taurus)
FMO1:FAD N-oxidises TAM (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
FMO2:FAD:Mg2+ S-oxidises MTZ (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
FMO3:FAD N-oxidises TMA to TMAO (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Phase II - Conjugation of compounds (Bos taurus)
Methylation (Bos taurus)
CYP1A2 S-demethylates 6MMP (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Arachidonic acid metabolism (Bos taurus)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Bos taurus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Bos taurus)
Linoleic acid (LA) metabolism (Bos taurus)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Bos taurus)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Bos taurus)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase I - Functionalization of compounds (Caenorhabditis elegans)
Cytochrome P450 - arranged by substrate type (Caenorhabditis elegans)
Fatty acids (Caenorhabditis elegans)
CYP2J2 oxidises ARA (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Caenorhabditis elegans)
CYP2S1 4-hydroxylates atRA (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Caenorhabditis elegans)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
CYP2C19 5-hydroxylates omeprazole (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
CYP2D6 4-hydroxylates debrisoquine (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Caenorhabditis elegans)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
CYP2F1 dehydrogenates 3-methylindole (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A13 (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A6 (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
FMO oxidises nucleophiles (Caenorhabditis elegans)
FMO1:FAD N-oxidises TAM (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
FMO2:FAD:Mg2+ S-oxidises MTZ (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
FMO3:FAD N-oxidises TMA to TMAO (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Arachidonic acid metabolism (Caenorhabditis elegans)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Caenorhabditis elegans)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Caenorhabditis elegans)
Linoleic acid (LA) metabolism (Caenorhabditis elegans)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Caenorhabditis elegans)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Caenorhabditis elegans)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Eicosanoids (Canis familiaris)
CYP4F8 19-hydroxylates PGH2 (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Fatty acids (Canis familiaris)
CYP2J2 oxidises ARA (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP4A11 12-hydroxylates DDCX (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Canis familiaris)
CYP2S1 4-hydroxylates atRA (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP2U1 19-hydroxylates ARA (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP3A43 6b-hydroxylates TEST (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP4F11 16-hydroxylates 3OH-PALM (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Vitamins (Canis familiaris)
CYP26A1,B1 4-hydroxylate atRA (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Canis familiaris)
CYP2D6 4-hydroxylates debrisoquine (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Canis familiaris)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP2F1 dehydrogenates 3-methylindole (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP3A4 can N-demethylate loperamide (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP3A4,5 oxidise AFB1 to AFXBO (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
CYP3A7 can 6beta-hydroxylate testosterone (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A13 (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A6 (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
FMO oxidises nucleophiles (Canis familiaris)
FMO1:FAD N-oxidises TAM (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
FMO2:FAD:Mg2+ S-oxidises MTZ (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
FMO3:FAD N-oxidises TMA to TMAO (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Arachidonic acid metabolism (Canis familiaris)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Canis familiaris)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Canis familiaris)
Linoleic acid (LA) metabolism (Canis familiaris)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Canis familiaris)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Canis familiaris)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
Cytochrome P450 - arranged by substrate type (Danio rerio)
Eicosanoids (Danio rerio)
CYP4F3 20-hydroxylates LTB4 (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
CYP4F8 19-hydroxylates PGH2 (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Fatty acids (Danio rerio)
CYP2J2 oxidises ARA (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Danio rerio)
CYP2S1 4-hydroxylates atRA (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
CYP3A43 6b-hydroxylates TEST (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
CYP4F11 16-hydroxylates 3OH-PALM (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Vitamins (Danio rerio)
CYP26A1,B1 4-hydroxylate atRA (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Danio rerio)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Danio rerio)
N-atom dealkylation of caffeine (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
N-hydroxylation of 4-aminobiphenyl (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
CYP2D6 4-hydroxylates debrisoquine (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Danio rerio)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
CYP2F1 dehydrogenates 3-methylindole (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
CYP3A4 can N-demethylate loperamide (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
CYP3A4,5 oxidise AFB1 to AFXBO (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
CYP3A7 can 6beta-hydroxylate testosterone (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A13 (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A6 (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
FMO oxidises nucleophiles (Danio rerio)
FMO1:FAD N-oxidises TAM (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
FMO2:FAD:Mg2+ S-oxidises MTZ (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
FMO3:FAD N-oxidises TMA to TMAO (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Phase II - Conjugation of compounds (Danio rerio)
Methylation (Danio rerio)
CYP1A2 S-demethylates 6MMP (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Arachidonic acid metabolism (Danio rerio)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Danio rerio)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Danio rerio)
Linoleic acid (LA) metabolism (Danio rerio)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Danio rerio)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Danio rerio)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
Cytochrome P450 - arranged by substrate type (Dictyostelium discoideum)
Fatty acids (Dictyostelium discoideum)
CYP2J2 oxidises ARA (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Dictyostelium discoideum)
CYP2S1 4-hydroxylates atRA (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
CYP2U1 19-hydroxylates ARA (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Dictyostelium discoideum)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
CYP2C19 5-hydroxylates omeprazole (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
CYP2D6 4-hydroxylates debrisoquine (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Dictyostelium discoideum)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
CYP2F1 dehydrogenates 3-methylindole (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A13 (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A6 (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
FMO oxidises nucleophiles (Dictyostelium discoideum)
FMO1:FAD N-oxidises TAM (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
FMO2:FAD:Mg2+ S-oxidises MTZ (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
FMO3:FAD N-oxidises TMA to TMAO (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Dictyostelium discoideum)
Fatty acid metabolism (Dictyostelium discoideum)
Arachidonic acid metabolism (Dictyostelium discoideum)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Dictyostelium discoideum)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Dictyostelium discoideum)
Linoleic acid (LA) metabolism (Dictyostelium discoideum)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Dictyostelium discoideum)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Dictyostelium discoideum)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase I - Functionalization of compounds (Drosophila melanogaster)
Cytochrome P450 - arranged by substrate type (Drosophila melanogaster)
Fatty acids (Drosophila melanogaster)
CYP2J2 oxidises ARA (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Drosophila melanogaster)
CYP2S1 4-hydroxylates atRA (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Drosophila melanogaster)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
CYP2C19 5-hydroxylates omeprazole (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
CYP2D6 4-hydroxylates debrisoquine (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Drosophila melanogaster)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
CYP2F1 dehydrogenates 3-methylindole (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A13 (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A6 (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Arachidonic acid metabolism (Drosophila melanogaster)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Drosophila melanogaster)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Drosophila melanogaster)
Linoleic acid (LA) metabolism (Drosophila melanogaster)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Drosophila melanogaster)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Drosophila melanogaster)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Cytochrome P450 - arranged by substrate type (Gallus gallus)
Fatty acids (Gallus gallus)
CYP2J2 oxidises ARA (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP4A11 12-hydroxylates DDCX (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Gallus gallus)
CYP2S1 4-hydroxylates atRA (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP2U1 19-hydroxylates ARA (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP3A43 6b-hydroxylates TEST (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Vitamins (Gallus gallus)
CYP26A1,B1 4-hydroxylate atRA (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Gallus gallus)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Gallus gallus)
N-atom dealkylation of caffeine (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
N-hydroxylation of 4-aminobiphenyl (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP2C19 5-hydroxylates omeprazole (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP2D6 4-hydroxylates debrisoquine (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Gallus gallus)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP3A4 can N-demethylate loperamide (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP3A4,5 oxidise AFB1 to AFXBO (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
CYP3A7 can 6beta-hydroxylate testosterone (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
FMO oxidises nucleophiles (Gallus gallus)
FMO3:FAD N-oxidises TMA to TMAO (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Phase II - Conjugation of compounds (Gallus gallus)
Methylation (Gallus gallus)
CYP1A2 S-demethylates 6MMP (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Gallus gallus)
Fatty acid metabolism (Gallus gallus)
Arachidonic acid metabolism (Gallus gallus)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Gallus gallus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Gallus gallus)
Linoleic acid (LA) metabolism (Gallus gallus)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Gallus gallus)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Gallus gallus)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Eicosanoids (Homo sapiens)
CYP4F3 20-hydroxylates LTB4 (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP4F8 19-hydroxylates PGH2 (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Fatty acids (Homo sapiens)
CYP2J2 oxidises ARA (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP4A11 12-hydroxylates DDCX (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Homo sapiens)
CYP2S1 4-hydroxylates atRA (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP2U1 19-hydroxylates ARA (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP3A43 6b-hydroxylates TEST (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP4F11 16-hydroxylates 3OH-PALM (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Vitamins (Homo sapiens)
CYP26A1,B1 4-hydroxylate atRA (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Homo sapiens)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Homo sapiens)
N-atom dealkylation of caffeine (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
N-hydroxylation of 4-aminobiphenyl (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP2C19 5-hydroxylates omeprazole (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP2D6 4-hydroxylates debrisoquine (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Homo sapiens)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP2F1 dehydrogenates 3-methylindole (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP3A4 can N-demethylate loperamide (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP3A4,5 oxidise AFB1 to AFXBO (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
CYP3A7 can 6beta-hydroxylate testosterone (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A13 (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A6 (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
FMO oxidises nucleophiles (Homo sapiens)
FMO1:FAD N-oxidises TAM (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
FMO2:FAD:Mg2+ S-oxidises MTZ (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
FMO3:FAD N-oxidises TMA to TMAO (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Phase II - Conjugation of compounds (Homo sapiens)
Methylation (Homo sapiens)
CYP1A2 S-demethylates 6MMP (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Arachidonic acid metabolism (Homo sapiens)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Homo sapiens)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Homo sapiens)
Linoleic acid (LA) metabolism (Homo sapiens)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Homo sapiens)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Homo sapiens)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Eicosanoids (Mus musculus)
CYP4F3 20-hydroxylates LTB4 (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP4F8 19-hydroxylates PGH2 (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Fatty acids (Mus musculus)
CYP2J2 oxidises ARA (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP4A11 12-hydroxylates DDCX (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Mus musculus)
CYP2S1 4-hydroxylates atRA (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP2U1 19-hydroxylates ARA (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP3A43 6b-hydroxylates TEST (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP4F11 16-hydroxylates 3OH-PALM (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Vitamins (Mus musculus)
CYP26A1,B1 4-hydroxylate atRA (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Mus musculus)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Mus musculus)
N-atom dealkylation of caffeine (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
N-hydroxylation of 4-aminobiphenyl (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP2C19 5-hydroxylates omeprazole (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP2D6 4-hydroxylates debrisoquine (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Mus musculus)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP2F1 dehydrogenates 3-methylindole (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP3A4 can N-demethylate loperamide (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP3A4,5 oxidise AFB1 to AFXBO (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
CYP3A7 can 6beta-hydroxylate testosterone (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A13 (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A6 (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
FMO oxidises nucleophiles (Mus musculus)
FMO1:FAD N-oxidises TAM (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
FMO2:FAD:Mg2+ S-oxidises MTZ (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
FMO3:FAD N-oxidises TMA to TMAO (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Phase II - Conjugation of compounds (Mus musculus)
Methylation (Mus musculus)
CYP1A2 S-demethylates 6MMP (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Arachidonic acid metabolism (Mus musculus)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Mus musculus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Mus musculus)
Linoleic acid (LA) metabolism (Mus musculus)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Mus musculus)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Mus musculus)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Plasmodium falciparum)
Metabolism of lipids (Plasmodium falciparum)
Fatty acid metabolism (Plasmodium falciparum)
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Plasmodium falciparum)
Linoleic acid (LA) metabolism (Plasmodium falciparum)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Plasmodium falciparum)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Plasmodium falciparum)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Plasmodium falciparum)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Eicosanoids (Rattus norvegicus)
CYP4F3 20-hydroxylates LTB4 (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP4F8 19-hydroxylates PGH2 (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Fatty acids (Rattus norvegicus)
CYP2J2 oxidises ARA (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP4A11 12-hydroxylates DDCX (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Rattus norvegicus)
CYP2S1 4-hydroxylates atRA (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP2U1 19-hydroxylates ARA (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP3A43 6b-hydroxylates TEST (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP4F11 16-hydroxylates 3OH-PALM (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Vitamins (Rattus norvegicus)
CYP26A1,B1 4-hydroxylate atRA (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Rattus norvegicus)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Rattus norvegicus)
N-atom dealkylation of caffeine (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
N-hydroxylation of 4-aminobiphenyl (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP2C19 5-hydroxylates omeprazole (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP2D6 4-hydroxylates debrisoquine (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Rattus norvegicus)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP2F1 dehydrogenates 3-methylindole (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP3A4 can N-demethylate loperamide (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP3A4,5 oxidise AFB1 to AFXBO (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
CYP3A7 can 6beta-hydroxylate testosterone (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A13 (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A6 (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
FMO oxidises nucleophiles (Rattus norvegicus)
FMO1:FAD N-oxidises TAM (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
FMO2:FAD:Mg2+ S-oxidises MTZ (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
FMO3:FAD N-oxidises TMA to TMAO (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Phase II - Conjugation of compounds (Rattus norvegicus)
Methylation (Rattus norvegicus)
CYP1A2 S-demethylates 6MMP (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Arachidonic acid metabolism (Rattus norvegicus)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Rattus norvegicus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Rattus norvegicus)
Linoleic acid (LA) metabolism (Rattus norvegicus)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Rattus norvegicus)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Rattus norvegicus)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Saccharomyces cerevisiae)
Metabolism of lipids (Saccharomyces cerevisiae)
Fatty acid metabolism (Saccharomyces cerevisiae)
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Saccharomyces cerevisiae)
Linoleic acid (LA) metabolism (Saccharomyces cerevisiae)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Saccharomyces cerevisiae)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Saccharomyces cerevisiae)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Saccharomyces cerevisiae)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Schizosaccharomyces pombe)
Metabolism of lipids (Schizosaccharomyces pombe)
Fatty acid metabolism (Schizosaccharomyces pombe)
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Schizosaccharomyces pombe)
Linoleic acid (LA) metabolism (Schizosaccharomyces pombe)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Schizosaccharomyces pombe)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Schizosaccharomyces pombe)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Schizosaccharomyces pombe)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Eicosanoids (Sus scrofa)
CYP4F3 20-hydroxylates LTB4 (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP4F8 19-hydroxylates PGH2 (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Fatty acids (Sus scrofa)
CYP2J2 oxidises ARA (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP4A11 12-hydroxylates DDCX (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Sus scrofa)
CYP2S1 4-hydroxylates atRA (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP2U1 19-hydroxylates ARA (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP3A43 6b-hydroxylates TEST (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP4F11 16-hydroxylates 3OH-PALM (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Vitamins (Sus scrofa)
CYP26A1,B1 4-hydroxylate atRA (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Sus scrofa)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 (Sus scrofa)
N-atom dealkylation of caffeine (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
N-hydroxylation of 4-aminobiphenyl (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP2C19 5-hydroxylates omeprazole (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP2D6 4-hydroxylates debrisoquine (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Sus scrofa)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP2F1 dehydrogenates 3-methylindole (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP3A4 can N-demethylate loperamide (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP3A4,5 oxidise AFB1 to AFXBO (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
CYP3A7 can 6beta-hydroxylate testosterone (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A13 (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A6 (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
FMO oxidises nucleophiles (Sus scrofa)
FMO1:FAD N-oxidises TAM (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
FMO2:FAD:Mg2+ S-oxidises MTZ (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
FMO3:FAD N-oxidises TMA to TMAO (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Phase II - Conjugation of compounds (Sus scrofa)
Methylation (Sus scrofa)
CYP1A2 S-demethylates 6MMP (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Arachidonic acid metabolism (Sus scrofa)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Sus scrofa)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Sus scrofa)
Linoleic acid (LA) metabolism (Sus scrofa)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Sus scrofa)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Sus scrofa)
NADP+ [endoplasmic reticulum lumen]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
Cytochrome P450 - arranged by substrate type (Xenopus tropicalis)
Eicosanoids (Xenopus tropicalis)
CYP4F3 20-hydroxylates LTB4 (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP4F8 19-hydroxylates PGH2 (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Fatty acids (Xenopus tropicalis)
CYP2J2 oxidises ARA (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP4A11 12-hydroxylates DDCX (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP4B1 12-hydroxylates ARA (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP4F12 18-hydroxylates ARA (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Miscellaneous substrates (Xenopus tropicalis)
CYP2S1 4-hydroxylates atRA (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP2U1 19-hydroxylates ARA (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP2W1 oxidises INDOL (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP3A43 6b-hydroxylates TEST (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP4F11 16-hydroxylates 3OH-PALM (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Vitamins (Xenopus tropicalis)
CYP26A1,B1 4-hydroxylate atRA (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Xenobiotics (Xenopus tropicalis)
CYP2D6 4-hydroxylates debrisoquine (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP2E1 reactions (Xenopus tropicalis)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Benzene is hydroxylated to phenol (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
MEOS oxidizes ethanol to acetaldehyde (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP2F1 dehydrogenates 3-methylindole (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP3A4 can N-demethylate loperamide (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP3A4,5 oxidise AFB1 to AFXBO (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
CYP3A7 can 6beta-hydroxylate testosterone (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A13 (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Coumarin is 7-hydroxylated by CYP2A6 (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
O-atom dealkylation of dextromethorphan (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
FMO oxidises nucleophiles (Xenopus tropicalis)
FMO1:FAD N-oxidises TAM (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
FMO2:FAD:Mg2+ S-oxidises MTZ (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
FMO3:FAD N-oxidises TMA to TMAO (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Metabolism of lipids (Xenopus tropicalis)
Fatty acid metabolism (Xenopus tropicalis)
Arachidonic acid metabolism (Xenopus tropicalis)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) (Xenopus tropicalis)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Xenopus tropicalis)
Linoleic acid (LA) metabolism (Xenopus tropicalis)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
alpha-linolenic acid (ALA) metabolism (Xenopus tropicalis)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Xenopus tropicalis)
NADP+ [endoplasmic reticulum lumen]
External Reference Information
External Reference
NADP(+) [ChEBI:18009]
Participates
as an input of
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Homo sapiens)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Mus musculus)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Rattus norvegicus)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Canis familiaris)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Bos taurus)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Sus scrofa)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Danio rerio)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Xenopus tropicalis)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Gallus gallus)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Drosophila melanogaster)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Caenorhabditis elegans)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Dictyostelium discoideum)
as an output of
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Plasmodium falciparum)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Saccharomyces cerevisiae)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Schizosaccharomyces pombe)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Dictyostelium discoideum)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Caenorhabditis elegans)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Drosophila melanogaster)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Gallus gallus)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Xenopus tropicalis)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Danio rerio)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Sus scrofa)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Bos taurus)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Canis familiaris)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Rattus norvegicus)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Mus musculus)
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Homo sapiens)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Dictyostelium discoideum)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Drosophila melanogaster)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Gallus gallus)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Xenopus tropicalis)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Danio rerio)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Sus scrofa)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Bos taurus)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Canis familiaris)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Rattus norvegicus)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Mus musculus)
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Dictyostelium discoideum)
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Drosophila melanogaster)
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Gallus gallus)
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Xenopus tropicalis)
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Danio rerio)
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Sus scrofa)
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Bos taurus)
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Canis familiaris)
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Rattus norvegicus)
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Mus musculus)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Plasmodium falciparum)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Saccharomyces cerevisiae)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Schizosaccharomyces pombe)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Dictyostelium discoideum)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Caenorhabditis elegans)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Drosophila melanogaster)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Gallus gallus)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Xenopus tropicalis)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Danio rerio)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Sus scrofa)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Bos taurus)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Canis familiaris)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Rattus norvegicus)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Mus musculus)
Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Homo sapiens)
Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Homo sapiens)
Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Homo sapiens)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Dictyostelium discoideum)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Caenorhabditis elegans)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Drosophila melanogaster)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Gallus gallus)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Xenopus tropicalis)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Danio rerio)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Sus scrofa)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Bos taurus)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Canis familiaris)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Rattus norvegicus)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Mus musculus)
Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Homo sapiens)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Dictyostelium discoideum)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Gallus gallus)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Xenopus tropicalis)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Danio rerio)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Sus scrofa)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Bos taurus)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Canis familiaris)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Rattus norvegicus)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Mus musculus)
Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Homo sapiens)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Gallus gallus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Danio rerio)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Sus scrofa)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Bos taurus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Canis familiaris)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Rattus norvegicus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Mus musculus)
Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Homo sapiens)
CYP26A1,B1 4-hydroxylate atRA (Gallus gallus)
CYP26A1,B1 4-hydroxylate atRA (Xenopus tropicalis)
CYP26A1,B1 4-hydroxylate atRA (Danio rerio)
CYP26A1,B1 4-hydroxylate atRA (Sus scrofa)
CYP26A1,B1 4-hydroxylate atRA (Bos taurus)
CYP26A1,B1 4-hydroxylate atRA (Canis familiaris)
CYP26A1,B1 4-hydroxylate atRA (Rattus norvegicus)
CYP26A1,B1 4-hydroxylate atRA (Mus musculus)
CYP26A1,B1 4-hydroxylate atRA (Homo sapiens)
CYP2D6 4-hydroxylates debrisoquine (Dictyostelium discoideum)
CYP2D6 4-hydroxylates debrisoquine (Caenorhabditis elegans)
CYP2D6 4-hydroxylates debrisoquine (Drosophila melanogaster)
CYP2D6 4-hydroxylates debrisoquine (Gallus gallus)
CYP2D6 4-hydroxylates debrisoquine (Xenopus tropicalis)
CYP2D6 4-hydroxylates debrisoquine (Danio rerio)
CYP2D6 4-hydroxylates debrisoquine (Sus scrofa)
CYP2D6 4-hydroxylates debrisoquine (Bos taurus)
CYP2D6 4-hydroxylates debrisoquine (Canis familiaris)
CYP2D6 4-hydroxylates debrisoquine (Rattus norvegicus)
CYP2D6 4-hydroxylates debrisoquine (Mus musculus)
CYP2D6 4-hydroxylates debrisoquine (Homo sapiens)
MEOS oxidizes ethanol to acetaldehyde (Dictyostelium discoideum)
MEOS oxidizes ethanol to acetaldehyde (Caenorhabditis elegans)
MEOS oxidizes ethanol to acetaldehyde (Drosophila melanogaster)
MEOS oxidizes ethanol to acetaldehyde (Gallus gallus)
MEOS oxidizes ethanol to acetaldehyde (Xenopus tropicalis)
MEOS oxidizes ethanol to acetaldehyde (Danio rerio)
MEOS oxidizes ethanol to acetaldehyde (Sus scrofa)
MEOS oxidizes ethanol to acetaldehyde (Bos taurus)
MEOS oxidizes ethanol to acetaldehyde (Canis familiaris)
MEOS oxidizes ethanol to acetaldehyde (Rattus norvegicus)
MEOS oxidizes ethanol to acetaldehyde (Mus musculus)
MEOS oxidizes ethanol to acetaldehyde (Homo sapiens)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Dictyostelium discoideum)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Caenorhabditis elegans)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Drosophila melanogaster)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Gallus gallus)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Xenopus tropicalis)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Danio rerio)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Sus scrofa)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Bos taurus)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Canis familiaris)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Rattus norvegicus)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Mus musculus)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Homo sapiens)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Dictyostelium discoideum)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Caenorhabditis elegans)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Drosophila melanogaster)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Gallus gallus)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Xenopus tropicalis)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Danio rerio)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Sus scrofa)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Bos taurus)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Canis familiaris)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Rattus norvegicus)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Mus musculus)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Homo sapiens)
Benzene is hydroxylated to phenol (Dictyostelium discoideum)
Benzene is hydroxylated to phenol (Caenorhabditis elegans)
Benzene is hydroxylated to phenol (Drosophila melanogaster)
Benzene is hydroxylated to phenol (Gallus gallus)
Benzene is hydroxylated to phenol (Xenopus tropicalis)
Benzene is hydroxylated to phenol (Danio rerio)
Benzene is hydroxylated to phenol (Sus scrofa)
Benzene is hydroxylated to phenol (Bos taurus)
Benzene is hydroxylated to phenol (Canis familiaris)
Benzene is hydroxylated to phenol (Rattus norvegicus)
Benzene is hydroxylated to phenol (Mus musculus)
Benzene is hydroxylated to phenol (Homo sapiens)
CYP2C19 5-hydroxylates omeprazole (Dictyostelium discoideum)
CYP2C19 5-hydroxylates omeprazole (Caenorhabditis elegans)
CYP2C19 5-hydroxylates omeprazole (Drosophila melanogaster)
CYP2C19 5-hydroxylates omeprazole (Gallus gallus)
CYP2C19 5-hydroxylates omeprazole (Sus scrofa)
CYP2C19 5-hydroxylates omeprazole (Bos taurus)
CYP2C19 5-hydroxylates omeprazole (Rattus norvegicus)
CYP2C19 5-hydroxylates omeprazole (Mus musculus)
CYP2C19 5-hydroxylates omeprazole (Homo sapiens)
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Dictyostelium discoideum)
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Caenorhabditis elegans)
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Drosophila melanogaster)
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Gallus gallus)
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Sus scrofa)
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Bos taurus)
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Rattus norvegicus)
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Mus musculus)
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Homo sapiens)
N-atom dealkylation of caffeine (Gallus gallus)
N-atom dealkylation of caffeine (Danio rerio)
N-atom dealkylation of caffeine (Sus scrofa)
N-atom dealkylation of caffeine (Bos taurus)
N-atom dealkylation of caffeine (Rattus norvegicus)
N-atom dealkylation of caffeine (Mus musculus)
N-atom dealkylation of caffeine (Homo sapiens)
CYP3A4,5 oxidise AFB1 to AFXBO (Gallus gallus)
CYP3A4,5 oxidise AFB1 to AFXBO (Xenopus tropicalis)
CYP3A4,5 oxidise AFB1 to AFXBO (Danio rerio)
CYP3A4,5 oxidise AFB1 to AFXBO (Sus scrofa)
CYP3A4,5 oxidise AFB1 to AFXBO (Bos taurus)
CYP3A4,5 oxidise AFB1 to AFXBO (Canis familiaris)
CYP3A4,5 oxidise AFB1 to AFXBO (Rattus norvegicus)
CYP3A4,5 oxidise AFB1 to AFXBO (Mus musculus)
CYP3A4,5 oxidise AFB1 to AFXBO (Homo sapiens)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Dictyostelium discoideum)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Caenorhabditis elegans)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Drosophila melanogaster)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Gallus gallus)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Xenopus tropicalis)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Danio rerio)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Sus scrofa)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Bos taurus)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Canis familiaris)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Rattus norvegicus)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Mus musculus)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Homo sapiens)
CYP3A4 can N-demethylate loperamide (Gallus gallus)
CYP3A4 can N-demethylate loperamide (Xenopus tropicalis)
CYP3A4 can N-demethylate loperamide (Danio rerio)
CYP3A4 can N-demethylate loperamide (Sus scrofa)
CYP3A4 can N-demethylate loperamide (Bos taurus)
CYP3A4 can N-demethylate loperamide (Canis familiaris)
CYP3A4 can N-demethylate loperamide (Rattus norvegicus)
CYP3A4 can N-demethylate loperamide (Mus musculus)
CYP3A4 can N-demethylate loperamide (Homo sapiens)
Coumarin is 7-hydroxylated by CYP2A13 (Dictyostelium discoideum)
Coumarin is 7-hydroxylated by CYP2A13 (Caenorhabditis elegans)
Coumarin is 7-hydroxylated by CYP2A13 (Drosophila melanogaster)
Coumarin is 7-hydroxylated by CYP2A13 (Xenopus tropicalis)
Coumarin is 7-hydroxylated by CYP2A13 (Danio rerio)
Coumarin is 7-hydroxylated by CYP2A13 (Sus scrofa)
Coumarin is 7-hydroxylated by CYP2A13 (Bos taurus)
Coumarin is 7-hydroxylated by CYP2A13 (Canis familiaris)
Coumarin is 7-hydroxylated by CYP2A13 (Rattus norvegicus)
Coumarin is 7-hydroxylated by CYP2A13 (Mus musculus)
Coumarin is 7-hydroxylated by CYP2A13 (Homo sapiens)
CYP3A7 can 6beta-hydroxylate testosterone (Gallus gallus)
CYP3A7 can 6beta-hydroxylate testosterone (Xenopus tropicalis)
CYP3A7 can 6beta-hydroxylate testosterone (Danio rerio)
CYP3A7 can 6beta-hydroxylate testosterone (Sus scrofa)
CYP3A7 can 6beta-hydroxylate testosterone (Bos taurus)
CYP3A7 can 6beta-hydroxylate testosterone (Canis familiaris)
CYP3A7 can 6beta-hydroxylate testosterone (Rattus norvegicus)
CYP3A7 can 6beta-hydroxylate testosterone (Mus musculus)
CYP3A7 can 6beta-hydroxylate testosterone (Homo sapiens)
O-atom dealkylation of dextromethorphan (Dictyostelium discoideum)
O-atom dealkylation of dextromethorphan (Caenorhabditis elegans)
O-atom dealkylation of dextromethorphan (Drosophila melanogaster)
O-atom dealkylation of dextromethorphan (Gallus gallus)
O-atom dealkylation of dextromethorphan (Xenopus tropicalis)
O-atom dealkylation of dextromethorphan (Danio rerio)
O-atom dealkylation of dextromethorphan (Sus scrofa)
O-atom dealkylation of dextromethorphan (Bos taurus)
O-atom dealkylation of dextromethorphan (Canis familiaris)
O-atom dealkylation of dextromethorphan (Rattus norvegicus)
O-atom dealkylation of dextromethorphan (Mus musculus)
O-atom dealkylation of dextromethorphan (Homo sapiens)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Dictyostelium discoideum)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Caenorhabditis elegans)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Drosophila melanogaster)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Gallus gallus)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Sus scrofa)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Bos taurus)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Rattus norvegicus)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Mus musculus)
CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Homo sapiens)
CYP2F1 dehydrogenates 3-methylindole (Dictyostelium discoideum)
CYP2F1 dehydrogenates 3-methylindole (Caenorhabditis elegans)
CYP2F1 dehydrogenates 3-methylindole (Drosophila melanogaster)
CYP2F1 dehydrogenates 3-methylindole (Xenopus tropicalis)
CYP2F1 dehydrogenates 3-methylindole (Danio rerio)
CYP2F1 dehydrogenates 3-methylindole (Sus scrofa)
CYP2F1 dehydrogenates 3-methylindole (Bos taurus)
CYP2F1 dehydrogenates 3-methylindole (Canis familiaris)
CYP2F1 dehydrogenates 3-methylindole (Rattus norvegicus)
CYP2F1 dehydrogenates 3-methylindole (Mus musculus)
CYP2F1 dehydrogenates 3-methylindole (Homo sapiens)
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Dictyostelium discoideum)
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Caenorhabditis elegans)
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Drosophila melanogaster)
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Gallus gallus)
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Sus scrofa)
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Bos taurus)
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Rattus norvegicus)
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Mus musculus)
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Homo sapiens)
Coumarin is 7-hydroxylated by CYP2A6 (Dictyostelium discoideum)
Coumarin is 7-hydroxylated by CYP2A6 (Caenorhabditis elegans)
Coumarin is 7-hydroxylated by CYP2A6 (Drosophila melanogaster)
Coumarin is 7-hydroxylated by CYP2A6 (Xenopus tropicalis)
Coumarin is 7-hydroxylated by CYP2A6 (Danio rerio)
Coumarin is 7-hydroxylated by CYP2A6 (Sus scrofa)
Coumarin is 7-hydroxylated by CYP2A6 (Bos taurus)
Coumarin is 7-hydroxylated by CYP2A6 (Canis familiaris)
Coumarin is 7-hydroxylated by CYP2A6 (Rattus norvegicus)
Coumarin is 7-hydroxylated by CYP2A6 (Mus musculus)
Coumarin is 7-hydroxylated by CYP2A6 (Homo sapiens)
CYP2J2 oxidises ARA (Dictyostelium discoideum)
CYP2J2 oxidises ARA (Caenorhabditis elegans)
CYP2J2 oxidises ARA (Drosophila melanogaster)
CYP2J2 oxidises ARA (Gallus gallus)
CYP2J2 oxidises ARA (Xenopus tropicalis)
CYP2J2 oxidises ARA (Danio rerio)
CYP2J2 oxidises ARA (Sus scrofa)
CYP2J2 oxidises ARA (Bos taurus)
CYP2J2 oxidises ARA (Canis familiaris)
CYP2J2 oxidises ARA (Rattus norvegicus)
CYP2J2 oxidises ARA (Mus musculus)
CYP2J2 oxidises ARA (Homo sapiens)
CYP4B1 12-hydroxylates ARA (Gallus gallus)
CYP4B1 12-hydroxylates ARA (Xenopus tropicalis)
CYP4B1 12-hydroxylates ARA (Sus scrofa)
CYP4B1 12-hydroxylates ARA (Bos taurus)
CYP4B1 12-hydroxylates ARA (Canis familiaris)
CYP4B1 12-hydroxylates ARA (Rattus norvegicus)
CYP4B1 12-hydroxylates ARA (Mus musculus)
CYP4B1 12-hydroxylates ARA (Homo sapiens)
CYP4F12 18-hydroxylates ARA (Xenopus tropicalis)
CYP4F12 18-hydroxylates ARA (Danio rerio)
CYP4F12 18-hydroxylates ARA (Sus scrofa)
CYP4F12 18-hydroxylates ARA (Bos taurus)
CYP4F12 18-hydroxylates ARA (Canis familiaris)
CYP4F12 18-hydroxylates ARA (Rattus norvegicus)
CYP4F12 18-hydroxylates ARA (Mus musculus)
CYP4F12 18-hydroxylates ARA (Homo sapiens)
CYP4A11 12-hydroxylates DDCX (Gallus gallus)
CYP4A11 12-hydroxylates DDCX (Xenopus tropicalis)
CYP4A11 12-hydroxylates DDCX (Sus scrofa)
CYP4A11 12-hydroxylates DDCX (Bos taurus)
CYP4A11 12-hydroxylates DDCX (Canis familiaris)
CYP4A11 12-hydroxylates DDCX (Rattus norvegicus)
CYP4A11 12-hydroxylates DDCX (Mus musculus)
CYP4A11 12-hydroxylates DDCX (Homo sapiens)
CYP4F8 19-hydroxylates PGH2 (Xenopus tropicalis)
CYP4F8 19-hydroxylates PGH2 (Danio rerio)
CYP4F8 19-hydroxylates PGH2 (Sus scrofa)
CYP4F8 19-hydroxylates PGH2 (Bos taurus)
CYP4F8 19-hydroxylates PGH2 (Canis familiaris)
CYP4F8 19-hydroxylates PGH2 (Rattus norvegicus)
CYP4F8 19-hydroxylates PGH2 (Mus musculus)
CYP4F8 19-hydroxylates PGH2 (Homo sapiens)
CYP4F3 20-hydroxylates LTB4 (Xenopus tropicalis)
CYP4F3 20-hydroxylates LTB4 (Danio rerio)
CYP4F3 20-hydroxylates LTB4 (Sus scrofa)
CYP4F3 20-hydroxylates LTB4 (Rattus norvegicus)
CYP4F3 20-hydroxylates LTB4 (Mus musculus)
CYP4F3 20-hydroxylates LTB4 (Homo sapiens)
CYP2U1 19-hydroxylates ARA (Dictyostelium discoideum)
CYP2U1 19-hydroxylates ARA (Gallus gallus)
CYP2U1 19-hydroxylates ARA (Xenopus tropicalis)
CYP2U1 19-hydroxylates ARA (Sus scrofa)
CYP2U1 19-hydroxylates ARA (Bos taurus)
CYP2U1 19-hydroxylates ARA (Canis familiaris)
CYP2U1 19-hydroxylates ARA (Rattus norvegicus)
CYP2U1 19-hydroxylates ARA (Mus musculus)
CYP2U1 19-hydroxylates ARA (Homo sapiens)
CYP4F11 16-hydroxylates 3OH-PALM (Xenopus tropicalis)
CYP4F11 16-hydroxylates 3OH-PALM (Danio rerio)
CYP4F11 16-hydroxylates 3OH-PALM (Sus scrofa)
CYP4F11 16-hydroxylates 3OH-PALM (Bos taurus)
CYP4F11 16-hydroxylates 3OH-PALM (Canis familiaris)
CYP4F11 16-hydroxylates 3OH-PALM (Rattus norvegicus)
CYP4F11 16-hydroxylates 3OH-PALM (Mus musculus)
CYP4F11 16-hydroxylates 3OH-PALM (Homo sapiens)
CYP3A43 6b-hydroxylates TEST (Gallus gallus)
CYP3A43 6b-hydroxylates TEST (Xenopus tropicalis)
CYP3A43 6b-hydroxylates TEST (Danio rerio)
CYP3A43 6b-hydroxylates TEST (Sus scrofa)
CYP3A43 6b-hydroxylates TEST (Bos taurus)
CYP3A43 6b-hydroxylates TEST (Canis familiaris)
CYP3A43 6b-hydroxylates TEST (Rattus norvegicus)
CYP3A43 6b-hydroxylates TEST (Mus musculus)
CYP3A43 6b-hydroxylates TEST (Homo sapiens)
CYP2W1 oxidises INDOL (Dictyostelium discoideum)
CYP2W1 oxidises INDOL (Caenorhabditis elegans)
CYP2W1 oxidises INDOL (Drosophila melanogaster)
CYP2W1 oxidises INDOL (Gallus gallus)
CYP2W1 oxidises INDOL (Xenopus tropicalis)
CYP2W1 oxidises INDOL (Danio rerio)
CYP2W1 oxidises INDOL (Sus scrofa)
CYP2W1 oxidises INDOL (Bos taurus)
CYP2W1 oxidises INDOL (Canis familiaris)
CYP2W1 oxidises INDOL (Rattus norvegicus)
CYP2W1 oxidises INDOL (Mus musculus)
CYP2W1 oxidises INDOL (Homo sapiens)
CYP2S1 4-hydroxylates atRA (Dictyostelium discoideum)
CYP2S1 4-hydroxylates atRA (Caenorhabditis elegans)
CYP2S1 4-hydroxylates atRA (Drosophila melanogaster)
CYP2S1 4-hydroxylates atRA (Gallus gallus)
CYP2S1 4-hydroxylates atRA (Xenopus tropicalis)
CYP2S1 4-hydroxylates atRA (Danio rerio)
CYP2S1 4-hydroxylates atRA (Sus scrofa)
CYP2S1 4-hydroxylates atRA (Bos taurus)
CYP2S1 4-hydroxylates atRA (Canis familiaris)
CYP2S1 4-hydroxylates atRA (Rattus norvegicus)
CYP2S1 4-hydroxylates atRA (Mus musculus)
CYP2S1 4-hydroxylates atRA (Homo sapiens)
FMO2:FAD:Mg2+ S-oxidises MTZ (Dictyostelium discoideum)
FMO2:FAD:Mg2+ S-oxidises MTZ (Caenorhabditis elegans)
FMO2:FAD:Mg2+ S-oxidises MTZ (Xenopus tropicalis)
FMO2:FAD:Mg2+ S-oxidises MTZ (Danio rerio)
FMO2:FAD:Mg2+ S-oxidises MTZ (Sus scrofa)
FMO2:FAD:Mg2+ S-oxidises MTZ (Bos taurus)
FMO2:FAD:Mg2+ S-oxidises MTZ (Canis familiaris)
FMO2:FAD:Mg2+ S-oxidises MTZ (Rattus norvegicus)
FMO2:FAD:Mg2+ S-oxidises MTZ (Mus musculus)
FMO2:FAD:Mg2+ S-oxidises MTZ (Homo sapiens)
FMO1:FAD N-oxidises TAM (Dictyostelium discoideum)
FMO1:FAD N-oxidises TAM (Caenorhabditis elegans)
FMO1:FAD N-oxidises TAM (Xenopus tropicalis)
FMO1:FAD N-oxidises TAM (Danio rerio)
FMO1:FAD N-oxidises TAM (Sus scrofa)
FMO1:FAD N-oxidises TAM (Bos taurus)
FMO1:FAD N-oxidises TAM (Canis familiaris)
FMO1:FAD N-oxidises TAM (Rattus norvegicus)
FMO1:FAD N-oxidises TAM (Mus musculus)
CYP1A2 S-demethylates 6MMP (Homo sapiens)
CYP1A2 S-demethylates 6MMP (Mus musculus)
CYP1A2 S-demethylates 6MMP (Rattus norvegicus)
CYP1A2 S-demethylates 6MMP (Bos taurus)
CYP1A2 S-demethylates 6MMP (Sus scrofa)
CYP1A2 S-demethylates 6MMP (Danio rerio)
CYP1A2 S-demethylates 6MMP (Gallus gallus)
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Homo sapiens)
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Mus musculus)
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Rattus norvegicus)
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Bos taurus)
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Sus scrofa)
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Danio rerio)
Ethylene is oxidized to Ethylene oxide by CYP1A1 (Gallus gallus)
N-hydroxylation of 4-aminobiphenyl (Homo sapiens)
N-hydroxylation of 4-aminobiphenyl (Mus musculus)
N-hydroxylation of 4-aminobiphenyl (Rattus norvegicus)
N-hydroxylation of 4-aminobiphenyl (Bos taurus)
N-hydroxylation of 4-aminobiphenyl (Sus scrofa)
N-hydroxylation of 4-aminobiphenyl (Danio rerio)
N-hydroxylation of 4-aminobiphenyl (Gallus gallus)
FMO3:FAD N-oxidises TMA to TMAO (Homo sapiens)
FMO3:FAD N-oxidises TMA to TMAO (Mus musculus)
FMO3:FAD N-oxidises TMA to TMAO (Rattus norvegicus)
FMO3:FAD N-oxidises TMA to TMAO (Canis familiaris)
FMO3:FAD N-oxidises TMA to TMAO (Bos taurus)
FMO3:FAD N-oxidises TMA to TMAO (Sus scrofa)
FMO3:FAD N-oxidises TMA to TMAO (Danio rerio)
FMO3:FAD N-oxidises TMA to TMAO (Xenopus tropicalis)
FMO3:FAD N-oxidises TMA to TMAO (Gallus gallus)
FMO3:FAD N-oxidises TMA to TMAO (Caenorhabditis elegans)
FMO3:FAD N-oxidises TMA to TMAO (Dictyostelium discoideum)
FMO1:FAD N-oxidises TAM (Homo sapiens)
Other forms of this molecule
NADP+ [mitochondrial intermembrane space]
NADP+ [cytoplasm]
NADP+ [phagolysosome]
NADP+ [extracellular region]
NADP+ [nuclear envelope]
NADP+ [peroxisomal matrix]
Cross References
Guide to Pharmacology - Ligands
3045
COMPOUND
C00006
PubChem Substance
8145192
HMDB Metabolite
HMDB0304435
ZINC
000008214733
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text