Reactome | SCP2 [peroxisomal matrix]

SCP2 [peroxisomal matrix]

Stable Identifier

R-HSA-2046067

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

peroxisomal matrix

Synonyms

SCPx thiolase (SCPX), Non-specific lipid-transfer protein, NLTP_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P22307 SCP2

Gene Names

SCP2

Chain

chain:1-547

Reference Genes

BioGPS Gene:6342 SCP2

COSMIC (genes):SCP2 SCP2

CTD Gene:6342 SCP2

dbSNP Gene:6342 SCP2

ENSEMBL:ENSG00000116171 SCP2

HGNC:10606 SCP2

KEGG Gene (Homo sapiens):6342 SCP2

Monarch:6342 SCP2

NCBI Gene:6342 SCP2

OMIM:184755 SCP2

UCSC:P22307 SCP2

Reference Transcript

Other Identifiers

0001850605

11734259_a_at

11745850_a_at

11756580_x_at

11761075_a_at

16664802

201339_s_at

211733_x_at

2336586

2336587

2336590

2336592

2336593

2336594

2336595

2336596

2336598

2336599

2336600

2336601

2336602

2336603

2336604

2336606

2336607

2336608

2336609

2336610

2336612

2336613

2336617

2336618

2336619

2336620

2336621

2336622

2336623

2336624

2336629

36688_at

59385_at

6342

7901513

90029_at

A_14_P129129

A_23_P126057

A_24_P156922

GE58925

GE84308

GO:0000062

GO:0003674

GO:0003824

GO:0003988

GO:0005102

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005777

GO:0005782

GO:0005783

GO:0005829

GO:0006605

GO:0006625

GO:0006629

GO:0006635

GO:0006694

GO:0006699

GO:0006701

GO:0006810

GO:0006869

GO:0007031

GO:0008150

GO:0008206

GO:0008289

GO:0008526

GO:0009056

GO:0009058

GO:0015031

GO:0015485

GO:0015914

GO:0015918

GO:0016020

GO:0016740

GO:0016746

GO:0016747

GO:0032367

GO:0032385

GO:0032934

GO:0032959

GO:0032991

GO:0033540

GO:0033814

GO:0036042

GO:0036109

GO:0043167

GO:0043226

GO:0043231

GO:0044281

GO:0045940

GO:0050632

GO:0050633

GO:0061024

GO:0070538

GO:0071071

GO:0072659

GO:0120009

GO:0120019

GO:0120020

GO:1901373

HMNXSV003020810

HMNXSV003035321

ILMN_1674955

ILMN_1694776

PH_hs_0004367

TC01000648.hg

U11313_at

g13543502_3p_at

g4506822_3p_s_at

Participates

as an input of

TYSND1 cleaves SCP2 (Homo sapiens)

as a member of

Cargo proteins containing PTS1 [peroxisomal matrix] (Homo sapiens)

Other forms of this molecule

SCP2(425-547) [peroxisomal matrix]

SCP2(1-424) [peroxisomal matrix]

SCP2 [cytosol]

Cross References

RefSeq

NP_001007100.1, NP_001007101.1, NP_001180546.1, NP_001007251.1, NP_002970.2, NP_001180528.1, NP_001007099.1, XP_016857535.1

OpenTargets

ENSG00000116171

IntEnz

2.3.1.176

HPA

ENSG00000116171-SCP2

ZINC - Substances

NLTP_HUMAN

GeneCards

P22307

ZINC target

P22307

Ensembl

ENST00000407246, ENST00000488965, ENSG00000116171, ENST00000435345, ENSP00000360564, ENST00000430330, ENSP00000434132, ENSP00000396413, ENSP00000384569, ENSP00000406636, ENSP00000435783, ENSP00000360569, ENSP00000360568, ENST00000371509, ENST00000528311, ENSP00000386214, ENST00000408941, ENST00000371513, ENST00000371514

PRO

P22307

Orphanet

17584

ZINC - Predictions - Purchasable

NLTP_HUMAN

PDB

1QND, 2C0L

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15645 PCH2			0.666	4
UniProt:P49817 Cav1	6	Cav1 [endocytic vesicle membrane] (R-MMU-535009) caveolin-1 [lipid droplet] (R-MMU-163603) Cav1 [lipid droplet] (R-MMU-163510) Cav1 [Golgi membrane] (R-MMU-204504) Cav1 [early endosome membrane] (R-MMU-5368451) Cav1 [plasma membrane] (R-MMU-534994)	0.463	3
UniProt:Q03135 CAV1	5	CAV1 [early endosome membrane] (R-HSA-5368451) CAV1 [plasma membrane] (R-HSA-534994) CAV1 [Golgi membrane] (R-HSA-204504) CAV1 [lipid droplet] (R-HSA-163510) CAV1 [endocytic vesicle membrane] (R-HSA-535009)	0.454	3