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SCP2 [peroxisomal matrix]
Stable Identifier
R-HSA-2046067
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
peroxisomal matrix
Synonyms
SCPx thiolase (SCPX), Non-specific lipid-transfer protein, NLTP_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (Homo sapiens)
alpha-linolenic acid (ALA) metabolism (Homo sapiens)
Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) (Homo sapiens)
SCP2 [peroxisomal matrix] (Homo sapiens)
Protein localization (Homo sapiens)
Peroxisomal protein import (Homo sapiens)
Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Homo sapiens)
Cargo proteins containing PTS1 [peroxisomal matrix] (Homo sapiens)
SCP2 [peroxisomal matrix] (Homo sapiens)
TYSND1 cleaves peroxisomal proteins (Homo sapiens)
TYSND1 cleaves SCP2 (Homo sapiens)
SCP2 [peroxisomal matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:P22307 SCP2
Gene Names
SCP2
Chain
chain:1-547
Reference Genes
BioGPS Gene:6342 SCP2
COSMIC (genes):SCP2 SCP2
CTD Gene:6342 SCP2
dbSNP Gene:6342 SCP2
ENSEMBL:ENSG00000116171 SCP2
ENSEMBL_homo_sapiens_GENE:ENSG00000116171 SCP2
HGNC:10606 SCP2
KEGG Gene (Homo sapiens):6342 SCP2
Monarch:6342 SCP2
NCBI Gene:6342 SCP2
OMIM:184755 SCP2
UCSC:P22307 SCP2
Reference Transcript
RefSeq:NM_001007099.2 SCP2
RefSeq:NM_002979.4 SCP2
RefSeq:NM_001007250.2 SCP2
RefSeq:NM_001193617.1 SCP2
RefSeq:NM_001007098.2 SCP2
RefSeq:NM_001007100.2 SCP2
RefSeq:NM_001193599.1 SCP2
RefSeq:XM_017002046.1 SCP2
Other Identifiers
0001850605
11734259_a_at
11745850_a_at
11756580_x_at
11761075_a_at
16664802
1QND
201339_s_at
211733_x_at
2336586
2336587
2336590
2336592
2336593
2336594
2336595
2336596
2336598
2336599
2336600
2336601
2336602
2336603
2336604
2336606
2336612
2336613
2336617
2336618
2336619
2336620
2336621
2336622
2336623
2336624
27101
27135
27317
2C0L
36688_at
59385_at
6342
7901513
90029_at
A_14_P129129
A_23_P126057
A_24_P156922
AAA03557
AAA03558
AAA03559
AAB24921
AAB41286
AAH05911
AAH67108
AC099677
AK294631
AK295214
AK308105
AL445183
BAG57810
BAG58208
BC005911
BC067108
CB997588
CCDS30719
CCDS41338
CCDS44149
CCDS44150
CCDS53317
CCDS53318
CCDS53319
CCDS572
CH471059
CR995014
E9PLD1
EAX06760
EAX06761
ENSG00000116171
ENSP00000360564
ENSP00000360568
ENSP00000360569
ENSP00000384569
ENSP00000386214
ENSP00000396413
ENSP00000406636
ENSP00000434132
ENSP00000435783
ENST00000371509
ENST00000371513
ENST00000371514
ENST00000407246
ENST00000408941
ENST00000430330
ENST00000435345
ENST00000488965
ENST00000528311
EntrezGene:6342
g13543502_3p_at
g4506822_3p_s_at
GE58925
GO:0000062
GO:0003674
GO:0003824
GO:0005102
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005777
GO:0005782
GO:0005829
GO:0006605
GO:0006625
GO:0006629
GO:0006694
GO:0006699
GO:0006810
GO:0006869
GO:0007031
GO:0008150
GO:0008289
GO:0009056
GO:0009058
GO:0015485
GO:0015914
GO:0016020
GO:0016740
GO:0016746
GO:0016747
GO:0032385
GO:0032991
GO:0033540
GO:0033814
GO:0036042
GO:0036109
GO:0043167
GO:0043226
GO:0043231
GO:0044281
GO:0050632
GO:0070538
GO:1901373
HGNC:10606
HPA027101
HPA027135
HPA027317
ILMN_1674955
ILMN_1694776
IPR003033
IPR016039
IPR020613
IPR020615
IPR020616
IPR020617
IPR036527
M55421
M75883
M75884
MIM:184755
MIM:613724
NM_001007098
NM_001007099
NM_001007100
NM_001007250
NM_001193599
NM_001193600
NM_001193617
NM_002979
NP_001007099
NP_001007100
NP_001007101
NP_001007251
NP_001180528
NP_001180529
NP_001180546
NP_002970
PF00108
PF02036
PF02803
PH_hs_0004367
S52450
SCP2
SCP2-201
SCP2-202
SCP2-203
SCP2-204
SCP2-205
SCP2-206
SCP2-207
SCP2-212
SCP2-213
TC01000648.hg
U11297
U11299
U11300
U11301
U11302
U11303
U11304
U11305
U11306
U11307
U11308
U11309
U11310
U11311
U11312
U11313
U11313_at
uc001cuq.3
uc001cur.3
uc001cut.3
uc001cuu.3
uc009vzi.3
uc010ono.3
uc010onp.3
uc057gqn.1
uc057gqo.1
UPI0000000C71
UPI0000130258
UPI000034E592
UPI00004703AF
UPI00004703B0
UPI0000D61F1F
UPI00017A730D
UPI0001DD3808
XM_005271103
XM_017002046
XP_005271160
XP_016857535
Participant Of
hasMember
Cargo proteins containing PTS1 [peroxisomal matrix]
input
TYSND1 cleaves SCP2
Other forms of this molecule
SCP2 [cytosol]
SCP2(1-424) [peroxisomal matrix]
SCP2(425-547) [peroxisomal matrix]
Inferred To
SCP2-1 [peroxisomal matrix] (Bos taurus)
SCP2-1 [peroxisomal matrix] (Caenorhabditis elegans)
SCP2-1 [peroxisomal matrix] (Canis familiaris)
SCP2-1 [peroxisomal matrix] (Danio rerio)
SCP2-1 [peroxisomal matrix] (Drosophila melanogaster)
SCP2-1 [peroxisomal matrix] (Gallus gallus)
SCP2-1 [peroxisomal matrix] (Saccharomyces cerevisiae)
SCP2-1 [peroxisomal matrix] (Taeniopygia guttata)
SCP2-1 [peroxisomal matrix] (Xenopus tropicalis)
Homologues of SCP2-1 [peroxisomal matrix] (Drosophila melanogaster)
Homologues of SCP2-1 [peroxisomal matrix] (Gallus gallus)
Scp2(1-547) [peroxisomal matrix] (Mus musculus)
Cross References
RefSeq
NP_001180546.1
,
NP_001007100.1
,
NP_001007101.1
,
XP_016857535.1
,
NP_001007251.1
,
NP_001180528.1
,
NP_002970.2
,
NP_001007099.1
OpenTargets
ENSG00000116171
ZINC - Substances
NLTP_HUMAN
GeneCards
P22307
DOCK Blaster
2C0L
ZINC target
P22307
PRO
P22307
BRENDA (Homo sapiens)
2.3.1.176
Orphanet
17584
ZINC - Predictions - Purchasable
NLTP_HUMAN
PDB
2C0L
,
1QND
HMDB Protein
HMDBP00440
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15645 PCH2
0.666
4
UniProt:Q03135 CAV1
5
CAV1 [early endosome membrane]
(R-HSA-5368451)
CAV1 [plasma membrane]
(R-HSA-534994)
CAV1 [Golgi membrane]
(R-HSA-204504)
CAV1 [endocytic vesicle membrane]
(R-HSA-535009)
CAV1 [lipid droplet]
(R-HSA-163510)
0.482
3
UniProt:P49817 Cav1
6
CAV1 [lipid droplet]
(R-MMU-163510)
caveolin-1 [lipid droplet]
(R-MMU-163603)
CAV1 [endocytic vesicle membrane]
(R-MMU-535009)
CAV1 [Golgi membrane]
(R-MMU-204504)
CAV1 [early endosome membrane]
(R-MMU-5368451)
CAV1 [plasma membrane]
(R-MMU-534994)
0.463
3
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