Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
ITGA3(33-1051) [plasma membrane]
Stable Identifier
R-HSA-204441
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Integrin alpha-3, ITA3_HUMAN, ITGA3
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
AGRN binds Integrins alphaVbeta1 (Other beta1-containing integrins) (Homo sapiens)
Agrin:Integrin alphaVbeta1 (other beta1) [plasma membrane] (Homo sapiens)
Integrins alphaVbeta1 (other beta 1) [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Integrins alphaVbeta1 (other beta 1) [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Homo sapiens)
BSG:Integrin alpha3beta1, alpha6beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1, alpha6beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Integrin alpha3beta1, alpha6beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 (Homo sapiens)
Endostatin:Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Homo sapiens)
Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 (Homo sapiens)
Integrin alpha3beta1, alpha4beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Integrin alpha3beta1, alpha4beta1:THBS1 trimer [plasma membrane] (Homo sapiens)
Integrin alpha3beta1, alpha4beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Tumstatin binds integrin alphaVbeta 3, alpha3beta1 (Homo sapiens)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Tumstatin:Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Homo sapiens)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Laminin interactions (Homo sapiens)
Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221) (Homo sapiens)
Integrin alpha3beta1, alpha6beta4 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Integrin alpha3beta1, alpha6beta4:Laminins-332, 511, 521, (211, 221) [plasma membrane] (Homo sapiens)
Integrin alpha3beta1, alpha6beta4 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Hemostasis (Homo sapiens)
Cell surface interactions at the vascular wall (Homo sapiens)
Basigin interactions (Homo sapiens)
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Homo sapiens)
BSG:Integrin alpha3beta1, alpha6beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1, alpha6beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Integrin alpha3beta1, alpha6beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by MET (Homo sapiens)
MET promotes cell motility (Homo sapiens)
MET activates PTK2 signaling (Homo sapiens)
PTK2 binds activated MET (Homo sapiens)
Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens)
Integrin alpha2beta1,alpha3beta1 [plasma membrane] (Homo sapiens)
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
ITGA3(33-1051) [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P26006 ITGA3
Gene Names
ITGA3, MSK18
Chain
signal peptide:1-32, chain:33-1051, chain:33-872, chain:876-1051
Reference Genes
BioGPS Gene:3675 ITGA3
COSMIC (genes):ITGA3 ITGA3
CTD Gene:3675 ITGA3
dbSNP Gene:3675 ITGA3
ENSEMBL:ENSG00000005884 ITGA3
ENSEMBL:ENSG00000005884.18 ITGA3
HGNC:6139 ITGA3
KEGG Gene (Homo sapiens):3675 ITGA3
Monarch:3675 ITGA3
NCBI Gene:3675 ITGA3
OMIM:605025 ITGA3
UCSC:P26006 ITGA3
Reference Transcript
RefSeq:NM_002204.3 ITGA3
Other Identifiers
11739145_a_at
11749035_a_at
11756790_a_at
16835672
3675
3726155
3726156
3726157
3726161
3726162
3726163
3726164
3726166
3726167
3726168
3726170
3726171
3726172
3726173
3726174
3726176
3726177
3726178
3726179
3726180
3726182
3726183
3726184
3726185
3726186
3726187
3726188
3726189
3726191
3726195
3726196
3726198
3726199
3726200
3726201
3726202
3726203
3726204
3726205
3726206
8008237
884_at
885_g_at
A_23_P55251
GE63379
GO:0001764
GO:0001968
GO:0002020
GO:0002376
GO:0003014
GO:0005178
GO:0005515
GO:0005518
GO:0005576
GO:0005615
GO:0005886
GO:0005925
GO:0007155
GO:0007160
GO:0007229
GO:0007266
GO:0007507
GO:0007613
GO:0008305
GO:0009410
GO:0009897
GO:0009986
GO:0010628
GO:0010634
GO:0010811
GO:0010976
GO:0016020
GO:0016323
GO:0017015
GO:0019904
GO:0022414
GO:0023052
GO:0030111
GO:0030154
GO:0030324
GO:0030426
GO:0030510
GO:0031345
GO:0031527
GO:0031594
GO:0033627
GO:0034330
GO:0034667
GO:0034698
GO:0035024
GO:0035640
GO:0042995
GO:0043226
GO:0043235
GO:0043236
GO:0043588
GO:0044877
GO:0045202
GO:0045211
GO:0046872
GO:0046982
GO:0048333
GO:0048471
GO:0048787
GO:0048856
GO:0048870
GO:0050877
GO:0050900
GO:0060076
GO:0060135
GO:0070062
GO:0070161
GO:0071944
GO:0072006
GO:0072659
GO:0097060
GO:0097062
GO:0097205
GO:0098609
GO:0098978
GO:0099173
GO:0099560
GO:1903078
GO:1990812
HMNXSV003014501
ILMN_1654074
M59911_at
TC17000654.hg
g4504746_3p_a_at
Participates
as a component of
Integrin alpha3beta1 [plasma membrane] (Homo sapiens)
Inferred To
im:7145180 [plasma membrane]
(Danio rerio)
ina-1 [plasma membrane]
(Caenorhabditis elegans)
itga3 [plasma membrane]
(Xenopus tropicalis)
mew [plasma membrane]
(Drosophila melanogaster)
ITGA3(33-1051) [plasma membrane]
(Bos taurus)
ITGA3(33-1051) [plasma membrane]
(Canis familiaris)
ITGA3(33-1051) [plasma membrane]
(Gallus gallus)
ITGA3(33-1051) [plasma membrane]
(Sus scrofa)
Itga3 [plasma membrane]
(Mus musculus)
Itga3 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_002195.1
Guide to Pharmacology - Targets
2442
OpenTargets
ENSG00000005884
ZINC - Substances
ITA3_HUMAN
GeneCards
P26006
HPA
ENSG00000005884-ITGA3
ZINC target
P26006
Ensembl
ENSP00000007722
,
ENST00000320031
,
ENST00000007722
,
ENSP00000315190
,
ENSG00000005884
PRO
P26006
Pharos - Targets
P26006
Orphanet
21420
ZINC - Predictions - Purchasable
ITA3_HUMAN
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P48509 CD151
2
CD151 [cytosol]
(R-HSA-446072)
CD151 [plasma membrane]
(R-HSA-913947)
0.69
6
UniProt:P21926 CD9
4
CD9 [plasma membrane]
(R-HSA-51717)
CD9 [endocytic vesicle membrane]
(R-HSA-5334774)
CD9 [clathrin-coated endocytic vesicle membrane]
(R-HSA-5334779)
CD9 [platelet alpha granule membrane]
(R-HSA-114585)
0.462
6
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text