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MYO9B [cytosol]
Stable Identifier
R-HSA-2029011
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Myosin-IXb, MYO9B_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Signaling by ROBO receptors (Homo sapiens)
SLIT2:ROBO1 increases RHOA activity (Homo sapiens)
MYO9B inactivates RHOA (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
SLIT2:ROBO1:MYO9B [plasma membrane] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
SLIT2-bound ROBO1 binds MYO9B (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
SLIT2:ROBO1:MYO9B [plasma membrane] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole (Homo sapiens)
Myosin [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
Myosin-Actin filaments [cytosol] (Homo sapiens)
Myosin [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
Role of myosins in phagosome formation (Homo sapiens)
Myosin [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
Myosin-Actin filaments [cytosol] (Homo sapiens)
Myosin [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GAPs stimulate CDC42 GTPase activity (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GAPs stimulate RAC1 GTPase activity (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GAPs stimulate RHOA GTPase activity (Homo sapiens)
RHOA GAPs [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
RHOA binds effectors at the plasma membrane (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB GAPs stimulate RHOB GTPase activity (Homo sapiens)
RHOB GAPs [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
RHOB binds effectors at the plasma membrane (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC GAPs stimulate RHOC GTPase activity (Homo sapiens)
RHOC GAPs [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
RHOC binds effectors at the plasma membrane (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
RHOC:GTP:RHOC effectors [plasma membrane] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
RHOF GTPase cycle (Homo sapiens)
RHOF GAPs stimulate RHOF GTPase activity (Homo sapiens)
RHOF GAPs [cytosol] (Homo sapiens)
MYO9B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13459 MYO9B
Gene Names
MYO9B, MYR5
Chain
initiator methionine:, chain:2-2157
Reference Genes
BioGPS Gene:4650 MYO9B
COSMIC (genes):MYO9B MYO9B
CTD Gene:4650 MYO9B
dbSNP Gene:4650 MYO9B
ENSEMBL:ENSG00000099331 MYO9B
ENSEMBL_homo_sapiens_GENE:ENSG00000099331.14 MYO9B
HGNC:7609 MYO9B
KEGG Gene (Homo sapiens):4650 MYO9B
Monarch:4650 MYO9B
NCBI Gene:4650 MYO9B
OMIM:602129 MYO9B
UCSC:Q13459 MYO9B
Reference Transcript
RefSeq:NM_004145.3 MYO9B
Other Identifiers
11744129_at
16859395
208452_PM_x_at
208452_x_at
214780_PM_s_at
214780_s_at
217297_PM_s_at
217297_s_at
33816_at
3823983
3823990
3823991
3824017
3824018
3824020
3824021
3824023
3824026
3824027
3824028
3824029
3824031
3824033
3824035
3824036
3824041
3824044
3824047
3824049
3824050
3824051
3824052
3824053
3824054
3824056
3824057
3824058
3824059
3824060
3824061
3824062
3824063
3824066
3824067
3824068
3824069
3824070
3824072
3824075
3824077
3824079
3824080
3824083
3824084
3824086
3824087
3824088
3824089
40539_at
4650
8026638
A_24_P246173
A_24_P922921
GE80827
GE87676
GO:0000146
GO:0000166
GO:0001726
GO:0003774
GO:0003779
GO:0003824
GO:0005096
GO:0005515
GO:0005516
GO:0005524
GO:0005737
GO:0005829
GO:0005856
GO:0005884
GO:0005938
GO:0007165
GO:0007266
GO:0008092
GO:0015629
GO:0016020
GO:0016459
GO:0016787
GO:0016887
GO:0023052
GO:0030027
GO:0030048
GO:0031267
GO:0035023
GO:0035385
GO:0035556
GO:0043226
GO:0043531
GO:0046872
GO:0048471
GO:0048495
GO:0048856
GO:0051015
GO:0051056
GO:0072673
GO:0098772
GO:0140657
HMNXSV003037593
HMNXSV003056343
Hs.159629.3.A1_3p_a_at
Hs.159629.4.A1_3p_a_at
ILMN_1672547
PH_hs_0009728
TC19000327.hg
TC19002020.hg
Participates
as a member of
RHOA GAPs [cytosol] (Homo sapiens)
RHOC GAPs [cytosol] (Homo sapiens)
RHOB GAPs [cytosol] (Homo sapiens)
as a candidate of
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
RAC1 GAPs [cytosol] (Homo sapiens)
RHOF GAPs [cytosol] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
Myosin [cytosol] (Homo sapiens)
as an input of
SLIT2-bound ROBO1 binds MYO9B (Homo sapiens)
as a component of
SLIT2:ROBO1:MYO9B [plasma membrane] (Homo sapiens)
Inferred To
MYO9B [cytosol]
(Bos taurus)
MYO9B [cytosol]
(Caenorhabditis elegans)
MYO9B [cytosol]
(Canis familiaris)
MYO9B [cytosol]
(Gallus gallus)
MYO9B [cytosol]
(Mus musculus)
MYO9B [cytosol]
(Rattus norvegicus)
MYO9B [cytosol]
(Sus scrofa)
MYO9B [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_004136.2
OpenTargets
ENSG00000099331
GeneCards
Q13459
HPA
ENSG00000099331-MYO9B
Ensembl
ENST00000682292
,
ENSP00000471457
,
ENST00000397274
,
ENST00000595618
,
ENSP00000380444
,
ENSP00000507803
,
ENSG00000099331
PRO
Q13459
Pharos - Targets
Q13459
HMDB Protein
HMDBP07829
PDB
5C5S
,
5HPY
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