Reactome | Mast Cell Carboxypeptidase hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-33) (Angiotensin-(1-9))

Mast Cell Carboxypeptidase hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-33) (Angiotensin-(1-9))

Stable Identifier

R-HSA-2028294

Type

Reaction [transition]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Mast Cell Carboxypeptidase Hydrolyzes Angiotensin I to Yield Angiotensin-(1-9)

ReviewStatus

5/5

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Mast Cell Carboxypeptidase hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-33) (Angiotensin-(1-9))

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Mast cell carboxypeptidase (CPA3) hydrolyzes a single amino acid residue from the C-terminus of angiotensin-(1-10) (angiotensin I) to yield angiotensin-(1-9).

Literature References

PubMed ID	Title	Journal	Year
2708524	Human mast cell carboxypeptidase. Purification and characterization Goldstein, SM, Kaempfer, CE, Kealey, JT, Wintroub, BU	J Clin Invest	1989
2443571	Detection and partial characterization of a human mast cell carboxypeptidase Goldstein, SM, Kaempfer, CE, Proud, D, Schwartz, LB, Irani, AM, Wintroub, BU	J Immunol	1987