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DSPGs are secreted
Stable Identifier
R-HSA-2022065
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Golgi lumen
,
extracellular region
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Homo sapiens)
Metabolism of carbohydrates and carbohydrate derivatives (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Chondroitin sulfate/dermatan sulfate metabolism (Homo sapiens)
DS-GAG biosynthesis (Homo sapiens)
DSPGs are secreted (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Various forms of dermatan sulfate are excreted from the cell once formed. The mechanism of transport is unknown but most likely involves the trans-golgi network (Silbert & Sugumaran 2002).
Literature References
PubMed ID
Title
Journal
Year
12512856
Biosynthesis of chondroitin/dermatan sulfate
Silbert, JE
,
Sugumaran, G
IUBMB Life
2002
Participants
Input
DSPGs [Golgi lumen]
(Homo sapiens)
Output
DSPGs [extracellular region]
(Homo sapiens)
Participates
as an event of
DS-GAG biosynthesis (Homo sapiens)
Event Information
Go Biological Process
protein secretion (0009306)
Orthologous Events
DSPGs are secreted (Bos taurus)
DSPGs are secreted (Canis familiaris)
DSPGs are secreted (Danio rerio)
DSPGs are secreted (Drosophila melanogaster)
DSPGs are secreted (Gallus gallus)
DSPGs are secreted (Mus musculus)
DSPGs are secreted (Rattus norvegicus)
DSPGs are secreted (Sus scrofa)
DSPGs are secreted (Xenopus tropicalis)
Authored
Jassal, B (2011-11-25)
Reviewed
D'Eustachio, P (2012-03-28)
Created
Jassal, B (2011-11-25)
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