Dermatan sulfate can be further sulfated on position 2 of iduronate

Stable Identifier
R-HSA-2022061
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Golgi membrane, Golgi lumen
ReviewStatus
5/5
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Dermatan sulfate can be further sulfated on position 2 of iduronate
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Uronyl 2-sulfotransferase (UST) catalyzes the transfer of sulfate from PAPS to position 2 of iduronyl residues in dermatan sulfate (Kobayashi et al. 1999).
Literature References
PubMed ID Title Journal Year
10187838 Molecular cloning and characterization of a human uronyl 2-sulfotransferase that sulfates iduronyl and glucuronyl residues in dermatan/chondroitin sulfate

Kobayashi, M, Sugumaran, G, Liu, J, Shworak, NW, Silbert, JE, Rosenberg, RD

J Biol Chem 1999
Participants
Input
Output
Participates
as an event of
Catalyst Activity

sulfotransferase activity of UST [Golgi membrane]

Physical Entity
UST [Golgi membrane] (Homo sapiens)
Activity
sulfotransferase activity (GO:0008146)
Orthologous Events
Dermatan sulfate can be further sulfated on position 2 of iduronate (Bos taurus)
Dermatan sulfate can be further sulfated on position 2 of iduronate (Canis familiaris)
Dermatan sulfate can be further sulfated on position 2 of iduronate (Drosophila melanogaster)
Dermatan sulfate can be further sulfated on position 2 of iduronate (Gallus gallus)
Dermatan sulfate can be further sulfated on position 2 of iduronate (Mus musculus)
Dermatan sulfate can be further sulfated on position 2 of iduronate (Rattus norvegicus)
Dermatan sulfate can be further sulfated on position 2 of iduronate (Sus scrofa)
Authored
Jassal, B  (2011-11-25)
Reviewed
D'Eustachio, P  (2012-03-28)
D'Eustachio, P  (2025-03-12)
Created
Jassal, B  (2011-11-25)
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