CHST15 transfers sulfate to (6-)GalNAc-4-sulfate

Stable Identifier
R-HSA-2018659
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Golgi membrane, Golgi lumen
Synonyms
Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15
ReviewStatus
5/5
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CHST15 transfers sulfate to (6-)GalNAc-4-sulfate
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Carbohydrate sulfotransferase 15 (CHST15) catalyses the transfer of one or more sulfate ions from PAPS to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin 4-sulfate (C4S) (Ohtake et al. 2003).
Literature References
PubMed ID Title Journal Year
12874280 A unique nonreducing terminal modification of chondroitin sulfate by N-acetylgalactosamine 4-sulfate 6-o-sulfotransferase

Kimata, K, Ohtake, S, Habuchi, O

J Biol Chem 2003
Participants
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Output
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as an event of
Catalyst Activity

N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity of CHST15 [Golgi membrane]

Physical Entity
CHST15 [Golgi membrane] (Homo sapiens)
Activity
N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity (GO:0050659)
Orthologous Events
CHST15 transfers sulfate to (6-)GalNAc-4-sulfate (Bos taurus)
CHST15 transfers sulfate to (6-)GalNAc-4-sulfate (Danio rerio)
CHST15 transfers sulfate to (6-)GalNAc-4-sulfate (Gallus gallus)
CHST15 transfers sulfate to (6-)GalNAc-4-sulfate (Mus musculus)
CHST15 transfers sulfate to (6-)GalNAc-4-sulfate (Rattus norvegicus)
CHST15 transfers sulfate to (6-)GalNAc-4-sulfate (Sus scrofa)
CHST15 transfers sulfate to (6-)GalNAc-4-sulfate (Xenopus tropicalis)
Cross References
RHEA
Authored
Jassal, B  (2011-11-24)
Reviewed
D'Eustachio, P  (2025-03-12)
D'Eustachio, P  (2012-03-28)
Created
Jassal, B  (2011-11-24)
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