Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15

Stable Identifier
R-HSA-2018659
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Golgi membrane, Golgi lumen
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Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15
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Carbohydrate sulfotransferase 15 (CHST15) catalyses the transfer of sulfate from PAPS to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin 4-sulfate (C4S) (Ohtake et al. 2003).

Literature References
PubMed ID Title Journal Year
12874280 A unique nonreducing terminal modification of chondroitin sulfate by N-acetylgalactosamine 4-sulfate 6-o-sulfotransferase

Ohtake, S, Kimata, K, Habuchi, O

J Biol Chem 2003
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity of CHST15 [Golgi membrane]
Physical Entity
CHST15 [Golgi membrane]
Activity
N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity (0050659)
Orthologous Events
Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Bos taurus)
Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Canis familiaris)
Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Danio rerio)
Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Gallus gallus)
Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Mus musculus)
Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Rattus norvegicus)
Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Sus scrofa)
Authored
Jassal, B  (2011-11-24)
Reviewed
D'Eustachio, P  (2012-03-28)
Created
Jassal, B  (2011-11-24)