Caspase-mediated cleavage of Acinus

Stable Identifier
R-HSA-201630
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Caspase-mediated cleavage of Acinus
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Acinus induces apoptotic chromatin condensation after cleavage and activation by CASP3 (Sahara et al., 1999).
Literature References
PubMed ID Title Journal Year
10490026 Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation

Sahara, S, Aoto, M, Eguchi, Y, Imamoto, N, Yoneda, Y, Tsujimoto, Y

Nature 1999
Participants
Input
Output
Participates
as an event of
Catalyst Activity

cysteine-type endopeptidase activity of Caspase-3 [cytosol]

Physical Entity
Caspase-3 [cytosol] (Homo sapiens)
Activity
cysteine-type endopeptidase activity (GO:0004197)
Orthologous Events
Caspase-mediated cleavage of Acinus (Bos taurus)
Caspase-mediated cleavage of Acinus (Canis familiaris)
Caspase-mediated cleavage of Acinus (Danio rerio)
Caspase-mediated cleavage of Acinus (Drosophila melanogaster)
Caspase-mediated cleavage of Acinus (Gallus gallus)
Caspase-mediated cleavage of Acinus (Mus musculus)
Caspase-mediated cleavage of Acinus (Rattus norvegicus)
Authored
Schulze-Osthoff, K  (2007-09-03)
Reviewed
Ranganathan, S  (2007-11-23)
Created
Matthews, L  (2007-09-03)
Cite Us!