Reactome | FLNC [cytosol]

FLNC [cytosol]

Stable Identifier

R-HSA-201585

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Filamin C

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q14315 FLNC

Gene Names

FLNC, ABPL, FLN2

Chain

chain:1-2725

Reference Genes

BioGPS Gene:2318 FLNC

COSMIC (genes):FLNC FLNC

CTD Gene:2318 FLNC

dbSNP Gene:2318 FLNC

ENSEMBL:ENSG00000128591 FLNC

HGNC:3756 FLNC

KEGG:hsa:2318 FLNC

Monarch:2318 FLNC

NCBI Gene:2318 FLNC

OMIM:102565 FLNC

UCSC:Q14315 FLNC

Reference Transcript

Other Identifiers

11720633_a_at

17051286

17124802

207876_PM_s_at

207876_s_at

2318

3023150

3023151

3023152

3023154

3023157

3023158

3023159

3023160

3023161

3023162

3023163

3023164

3023165

3023166

3023167

3023168

3023169

3023170

3023171

3023172

3023173

3023174

3023175

3023176

3023177

3023178

3023179

3023181

3023182

3023183

3023184

3023185

3023186

3023187

3023189

3023190

3023191

3023192

3023193

3023194

3023195

3023196

3023197

3023198

3023199

3023200

3023202

3023203

3023204

3023205

3023206

3023207

3023208

3023209

3023210

3023212

3023213

3023214

3023215

3071986

3071988

3071989

3071990

35330_at

8135990

A_14_P122581

A_24_P77968

GE81024

GO:0003779

GO:0005515

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005925

GO:0007010

GO:0008092

GO:0016020

GO:0016528

GO:0030018

GO:0030036

GO:0030506

GO:0042383

GO:0042802

GO:0043034

GO:0043226

GO:0043232

GO:0045171

GO:0045214

GO:0048856

GO:0051015

GO:0055001

HMNXSV003044698

ILMN_1715748

PH_hs_0003757

PH_hs_0004512

PH_hs_0035465

TC07000785.hg

TC07003161.hg

X70083_at

g4557596_3p_a_at

Participates

as a member of

Filamin [cytosol] (Homo sapiens)

Inferred To

cher [cytosol] (Drosophila melanogaster)

fln-1 [cytosol] (Caenorhabditis elegans)

flnc [cytosol] (Xenopus tropicalis)

FLNC [cytosol] (Bos taurus)

FLNC [cytosol] (Canis familiaris)

FLNC [cytosol] (Sus scrofa)

Flnc [cytosol] (Mus musculus)

Flnc [cytosol] (Rattus norvegicus)

abpC [cytosol] (Dictyostelium discoideum)

Cross References

ENSEMBL

ENSG00000128591, ENST00000325888, ENST00000346177, ENSP00000327145, ENSP00000344002

OpenTargets

ENSG00000128591

GeneCards

FLNC

HPA

ENSG00000128591-FLNC

PRO

Q14315

Pharos - Targets

Q14315

GlyGen

Q14315

Orphanet

FLNC

PDB

7P0E, 4MGX, 2D7N, 2D7O, 2NQC, 2D7M, 2D7Q, 2D7P, 1V05, 8PA0, 7OUU, 3V8O, 7OUV, 2K9U

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92629 SGCD	3	SGCD [endoplasmic reticulum membrane] (R-HSA-9913186) SGCD [Golgi membrane] (R-HSA-9913195) SGCD [plasma membrane] (R-HSA-9630711)	0.593	4
UniProt:O75923 DYSF	1	DYSF [cytoplasmic vesicle membrane] (R-HSA-5263626)	0.505	3
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	13

© 2025 Reactome

Cite Us!