Reactome | PCOLCE [extracellular region]

PCOLCE [extracellular region]

Stable Identifier

R-HSA-2002444

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

PCPE1, Procollagen C-endopeptidase enhancer 1, PCOC1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q15113 PCOLCE

Gene Names

PCOLCE, PCPE1

Chain

signal peptide:1-25, chain:26-449

Reference Genes

BioGPS Gene:5118 PCOLCE

COSMIC (genes):PCOLCE PCOLCE

CTD Gene:5118 PCOLCE

dbSNP Gene:5118 PCOLCE

ENSEMBL:ENSG00000106333 PCOLCE

ENSEMBL_homo_sapiens_GENE:ENSG00000106333.13 PCOLCE

HGNC:8738 PCOLCE

KEGG Gene (Homo sapiens):5118 PCOLCE

Monarch:5118 PCOLCE

NCBI Gene:5118 PCOLCE

OMIM:600270 PCOLCE

UCSC:Q15113 PCOLCE

Reference Transcript

RefSeq:NM_002593.3 PCOLCE

Other Identifiers

11715652_a_at

17049408

202465_PM_at

202465_at

3015683

3015684

3015686

3015687

3015693

3015696

3015699

3015700

3015701

3015702

3015703

31609_s_at

5118

8134869

A_23_P251499

GE62586

GO:0005198

GO:0005201

GO:0005515

GO:0005518

GO:0005576

GO:0005615

GO:0006508

GO:0008201

GO:0016504

GO:0030312

GO:0031012

GO:0032964

GO:0043226

GO:0062023

GO:0070062

GO:0098772

HMNXSV003017153

L33799_at

PH_hs_0011876

TC07000627.hg

g7262388_3p_at

Participates

as a member of

PCOLCEs [extracellular region] (Homo sapiens)

as a component of

TLL2:PCPE1 [extracellular region] (Homo sapiens)

Inferred To

Pcolce [extracellular region] (Mus musculus)

Pcolce [extracellular region] (Rattus norvegicus)

pcolceb [extracellular region] (Danio rerio)

PCOLCE [extracellular region] (Bos taurus)

PCOLCE [extracellular region] (Caenorhabditis elegans)

PCOLCE [extracellular region] (Canis familiaris)

PCOLCE [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_002584.2

OpenTargets

ENSG00000106333

GeneCards

Q15113

HPA

ENSG00000106333-PCOLCE

Ensembl

ENST00000223061, ENSG00000106333, ENSP00000223061

PRO

Q15113

Pharos - Targets

Q15113

PDB

6FZW, 6FZV, 1UAP

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P43407 Sdc2	20	Sdc2 [plasma membrane] (R-MMU-2090052) phospho-Sdc2 [plasma membrane] (R-MMU-4093306) Sdc2 [lysosomal lumen] (R-MMU-2090083) Sdc2 [lysosomal lumen] (R-MMU-2090064) Sdc2 [Golgi lumen] (R-MMU-2076588) Sdc2 [Golgi lumen] (R-MMU-2076320) HS(2)-Sdc2 [Golgi lumen] (R-MMU-2161438) HS(1)-Sdc2 [Golgi lumen] (R-MMU-2161462) Sdc2 [Golgi lumen] (R-MMU-2076608) Sdc2 [Golgi lumen] (R-MMU-2076536) Sdc2 [plasma membrane] (R-MMU-2076683) Sdc2 [plasma membrane] (R-MMU-2076661) Sdc2 [plasma membrane] (R-MMU-2076644) Sdc2 [plasma membrane] (R-MMU-2076643) Sdc2 [plasma membrane] (R-MMU-2076631) Sdc2 [plasma membrane] (R-MMU-2076665) Sdc2 [endoplasmic reticulum lumen] (R-MMU-8956741) phospho-Sdc2 [endoplasmic reticulum lumen] (R-MMU-8956945) Sdc2 [Golgi lumen] (R-MMU-2064109) Sdc2 [Golgi lumen] (R-MMU-2064132)	0.576	4
UniProt:P07996 THBS1	5	THBS1 [extracellular region] (R-HSA-66518) THBS1 [platelet alpha granule lumen] (R-HSA-114701) O-fuc-THBS1 [endoplasmic reticulum lumen] (R-HSA-5173278) glc-fuc-THBS1 [endoplasmic reticulum lumen] (R-HSA-5172997) THBS1 [endoplasmic reticulum lumen] (R-HSA-5173263)	0.558	3
UniProt:P18828 Sdc1	20	HS(2)-Sdc1 [extracellular region] (R-MMU-2731129) HS(1)-Sdc1 [extracellular region] (R-MMU-2731145) Sdc1 [lysosomal lumen] (R-MMU-2090025) Sdc1 [lysosomal lumen] (R-MMU-2090082) Sdc1 [Golgi lumen] (R-MMU-2076520) Sdc1 [Golgi lumen] (R-MMU-2076290) HS(2)-Sdc1 [Golgi lumen] (R-MMU-2161443) HS(1)-Sdc1 [Golgi lumen] (R-MMU-2161455) Sdc1 [Golgi lumen] (R-MMU-2076561) Sdc1 [plasma membrane] (R-MMU-2076693) Sdc1 [plasma membrane] (R-MMU-2076652) Sdc1 [plasma membrane] (R-MMU-2076666) Sdc1 [plasma membrane] (R-MMU-2076672) Sdc1 [plasma membrane] (R-MMU-2076691) Sdc1 [plasma membrane] (R-MMU-2076626) Sdc1 [plasma membrane] (R-MMU-174758) Sdc1 [Golgi lumen] (R-MMU-2064146) Sdc1 [Golgi lumen] (R-MMU-2064148) Sdc1 [Golgi lumen] (R-MMU-2054105) Sdc1 [Golgi lumen] (R-MMU-2064247)	0.499	4

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