Reactome | RPE dimers isomerize XY5P to RU5P

RPE dimers isomerize XY5P to RU5P

Stable Identifier

R-HSA-199803

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

Synonyms

xylulose 5-phosphate <=> D-ribulose 5-phosphate

ReviewStatus

5/5

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Cytosolic ribulose-5-phosphate-3-epimerase (RPE) catalyzes the reversible interconversion of D-xylulose 5-phosphate and D-ribulose 5-phosphate (Bose and 1985). The electrophoretic properties of RPE activity detected in extracts of mouse-human somatic cell hybrids suggest that the active form of the enzyme is a homodimer (Spencer and Hopkinson 1980).

Literature References

PubMed ID	Title	Journal	Year
2581946	Phosphoribosylpyrophosphate synthesis from glucose decreases during amino acid starvation of human lymphoblasts Boss, GR, Pilz, RB	J Biol Chem	1985
7396409	Biochemical genetics of the pentose phosphate cycle: human ribose 5-phosphate isomerase (RPI) and ribulose 5-phosphate 3-epimerase (RPE) Spencer, N, Hopkinson, DA	Ann Hum Genet	1980