Overexpressed FGFR1 homodimers [plasma membrane]

Stable Identifier
Set [DefinedSet]
Homo sapiens
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
16807070 Recurrent FGFR1 amplification and high FGFR1 protein expression in oral squamous cell carcinoma (OSCC)

Hofele, C, Flechtenmacher, C, Schwaenen, C, Mühling, J, Lichter, P, Sticht, C, Radlwimmer, B, Freier, K, Joos, S

Oral Oncol 2007
17699850 High-resolution single nucleotide polymorphism array analysis of epithelial ovarian cancer reveals numerous microdeletions and amplifications

Sridhar, A, Campbell, IG, Choong, DY, Qiu, W, Jacobs, S, Gorringe, KL, Thompson, ER

Clin Cancer Res 2007
19235922 Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development

Missiaglia, E, Pritchard-Jones, K, Schaaf, G, Selfe, J, Summersgill, B, Versteeg, R, Williamson, D, Hamdi, M, Fang, C, Kool, M, Koster, J, Messahel, B, Shipley, J

Genes Chromosomes Cancer 2009
11389083 High-throughput tissue microarray analysis of 3p25 (RAF1) and 8p12 (FGFR1) copy number alterations in urinary bladder cancer

Jäger, P, Hardmeier, T, Ackermann, D, Wagner, U, Flury, R, Maurer, R, Sauter, G, Knönagel, H, Alund, G, Anabitarte, M, Gasser, T, Hering, F, Moch, H, Schmid, U, Wilber, K, Mihatsch, MJ, Schraml, P, Schönenberger, A, Richter, J, Simon, R, Rist, M, Fehr, JL, Bruderer, J, Fijan, A

Cancer Res 2001
17121884 FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

Sarrio, D, Hardisson, D, Savage, K, Weber, B, Schmitt, FC, Ashworth, A, Lambros, MB, Reis-Filho, JS, Dexter, T, Iravani, M, Turner, NC, Jones, C, Fenwick, K, Grigoriadis, A, Lakhani, SR, Palacios, J, Simpson, PT, Mackay, A

Clin Cancer Res 2006
21160078 Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer

Sietsma, H, Smit, E, Solomon, B, Sollberg, S, Soltermann, A, Sos, ML, Stoelben, E, Thomas, RK, Sänger, J, Timens, W, Thunnissen, E, Wagener, P, Cappuzzo, F, Buettner, R, Brustugun, OT, Brambilla, E, Brambilla, C, Baumann, M, Beroukhim, R, Baessmann, I, Balke-Want, H, Ansén, S, Altmüller, J, Zander, T, Wright, G, Leenders, F, Koker, M, Heynck, S, Klebl, B, Heukamp, LC, Heuckmann, JM, Hallek, M, Heideman, D, Groen, H, Fischer, F, Gabler, F, Ernestus, K, Engel-Riedel, W, Damiani, S, Conron, M, Dabow, I, Clement, J, Seidel, D, Schöttle, J, Russell, P, Rauh, D, Petersen, I, Querings, S, Perner, S, Nürnberg, P, Peifer, M, Moch, H, Menon, R, Ludwig, C, Maier, S, Ligorio, C, Lorimier, P, Wolf, J, Pao, W, Weiss, J, Wainer, Z, Ullrich, RT

Sci Transl Med 2010
7927944 Expression of the FGFR1 gene in human breast-carcinoma cells

deLapeyriere, O, Adelaide, J, Birnbaum, D, Parc, P, Penault-Llorca, F, Jacquemier, J, Planche, J

Int J Cancer 1994
21666749 Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer

Mermel, C, Hammerman, PS, Greulich, H, Gray, NS, Ramos, AH, Cho, J, Chande, A, Dutt, A, Tanaka, KE, Stransky, N, Meyerson, M, Sharifnia, T

PLoS One 2011
Name Identifier Synonyms
rhabdomyosarcoma DOID:3247 Rhabdomyosarcoma NOS (morphologic abnormality), rhabdomyosarcoma, Rhabdomyosarcoma, no subtype (morphologic abnormality), rhabdomyoblastoma, Rhabdomyosarcoma (disorder)
bladder carcinoma DOID:4007 carcinoma of urinary bladder, carcinoma bladder, carcinoma OF BLADDER, carcinoma of bladder (disorder), carcinoma bladder
ovarian cancer DOID:2394 ovarian neoplasm, malignant tumour of ovary, neoplasm of ovary (disorder), ovary neoplasm, primary malignant neoplasm of ovary and other uterine adnexa (disorder), ovarian cancer, tumor of the Ovary, ovary cancer, malignant Ovarian tumor, primary ovarian cancer, malignant tumor of ovary (disorder)
breast cancer DOID:1612 malignant tumor of the breast, mammary cancer, malignant neoplasm of breast, mammary tumor, primary breast cancer, breast cancer, Ca breast - NOS, breast tumor
head and neck squamous cell carcinoma DOID:5520 carcinoma of the head and neck, squamous cell carcinoma of the head and neck
lung squamous cell carcinoma DOID:3907 squamous cell carcinoma of lung (disorder), Epidermoid cell carcinoma of the lung
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