FGFR1c ligand binding and activation

Stable Identifier
R-HSA-190373
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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FGFR1c ligand binding and activation
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This pathway depicts the binding of an experimentally-verified range of ligands to FGFR1c. While binding affinities may vary considerably within this set, the ligands listed have been established to bring about receptor activation at their reported physiological concentrations.

Literature References
PubMed ID Title Journal Year
16597617 Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.

Ornitz, DM, Umemori, H, Mohammadi, M, Olsen, SK, Ibrahimi, OA, Zhang, X

J Biol Chem 2006
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
fibroblast growth factor receptor signaling pathway (0008543)
Orthologous Events
FGFR1c ligand binding and activation (Bos taurus)
FGFR1c ligand binding and activation (Caenorhabditis elegans)
FGFR1c ligand binding and activation (Canis familiaris)
FGFR1c ligand binding and activation (Danio rerio)
FGFR1c ligand binding and activation (Drosophila melanogaster)
FGFR1c ligand binding and activation (Gallus gallus)
FGFR1c ligand binding and activation (Mus musculus)
FGFR1c ligand binding and activation (Rattus norvegicus)
FGFR1c ligand binding and activation (Sus scrofa)
FGFR1c ligand binding and activation (Xenopus tropicalis)
Authored
de Bono, B  (2007-01-10)
Reviewed
Mohammadi, M  (2007-02-07)
Grose, RP  (2016-01-06)
Created
de Bono, B  (2007-01-02)
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