FGFR4 ligand binding and activation

Stable Identifier
R-HSA-190322
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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FGFR4 ligand binding and activation
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FGFR4 is expressed mainly in mature skeletal muscle, and disruption of FGFR4 signaling interrupts limb muscle formation in vertebrates.
Literature References
PubMed ID Title Journal Year
1385111 Fibroblast growth factor receptor-4 shows novel features in genomic structure, ligand binding and signal transduction

Alitalo, K, Jaye, M, Basilico, C, Coulier, F, Partanen, J, Birnbaum, D, Vainikka, S, Bellosta, P

EMBO J 1992
7518429 Signal transduction by fibroblast growth factor receptor-4 (FGFR-4). Comparison with FGFR-1

Alitalo, K, Wennström, S, Vainikka, S, Pelicci, PG, Joukov, V, Bergman, M

J Biol Chem 1994
16597617 Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.

Ornitz, DM, Umemori, H, Mohammadi, M, Olsen, SK, Ibrahimi, OA, Zhang, X

J Biol Chem 2006
15467729 Distinct transcriptional control and action of fibroblast growth factor receptor 4 in differentiating skeletal muscle cells

Asa, SL, Trinh, DK, Yu, S, Zheng, L, Ezzat, S

Lab Invest 2004
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
fibroblast growth factor receptor signaling pathway (0008543)
Orthologous Events
FGFR4 ligand binding and activation (Bos taurus)
FGFR4 ligand binding and activation (Caenorhabditis elegans)
FGFR4 ligand binding and activation (Canis familiaris)
FGFR4 ligand binding and activation (Danio rerio)
FGFR4 ligand binding and activation (Drosophila melanogaster)
FGFR4 ligand binding and activation (Gallus gallus)
FGFR4 ligand binding and activation (Mus musculus)
FGFR4 ligand binding and activation (Rattus norvegicus)
FGFR4 ligand binding and activation (Sus scrofa)
FGFR4 ligand binding and activation (Xenopus tropicalis)
Authored
de Bono, B  (2007-01-10)
Reviewed
Mohammadi, M  (2007-02-07)
Created
de Bono, B  (2007-01-02)
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