PDGF dimer binds two receptors simultaneously

Stable Identifier
R-HSA-186773
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
plasma membrane
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PDGF dimer binds two receptors simultaneously
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PDGF dimer binds two receptors simultaneously. The receptors dimerise on binding and this is key to receptor autophosphorylation.

Literature References
PubMed ID Title Journal Year
9739761 Signal transduction via platelet-derived growth factor receptors

Heldin, CH, Ostman, A, Rönnstrand, L

Biochim Biophys Acta 1998
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Output
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Orthologous Events
PDGF dimer binds two receptors simultaneously (Bos taurus)
PDGF dimer binds two receptors simultaneously (Caenorhabditis elegans)
PDGF dimer binds two receptors simultaneously (Canis familiaris)
PDGF dimer binds two receptors simultaneously (Danio rerio)
PDGF dimer binds two receptors simultaneously (Drosophila melanogaster)
PDGF dimer binds two receptors simultaneously (Gallus gallus)
PDGF dimer binds two receptors simultaneously (Mus musculus)
PDGF dimer binds two receptors simultaneously (Rattus norvegicus)
PDGF dimer binds two receptors simultaneously (Sus scrofa)
PDGF dimer binds two receptors simultaneously (Xenopus tropicalis)
Authored
Garapati, P V  (2008-11-24)
Jassal, B  (2008-11-24)
Reviewed
Heldin, CH  (2008-11-24)
Created
Jassal, B  (2006-08-15)