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PDGFRA:olaratumab [plasma membrane]
Stable Identifier
R-HSA-9674011
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PDGF (Homo sapiens)
Olaratumab binds PDGFRA (Homo sapiens)
PDGFRA:olaratumab [plasma membrane] (Homo sapiens)
PDGF dimer binds two receptors simultaneously (Homo sapiens)
PDGFRA:olaratumab [plasma membrane] (Homo sapiens)
Participants
components
olaratumab [extracellular region]
PDGFRA [plasma membrane]
(Homo sapiens)
Participates
as an output of
Olaratumab binds PDGFRA (Homo sapiens)
This entity regulates
Negatively
PDGF dimer binds two receptors simultaneously
(Homo sapiens)
Inferred To
PDGFRA:olaratumab [plasma membrane]
(Bos taurus)
PDGFRA:olaratumab [plasma membrane]
(Caenorhabditis elegans)
PDGFRA:olaratumab [plasma membrane]
(Canis familiaris)
PDGFRA:olaratumab [plasma membrane]
(Danio rerio)
PDGFRA:olaratumab [plasma membrane]
(Drosophila melanogaster)
PDGFRA:olaratumab [plasma membrane]
(Gallus gallus)
PDGFRA:olaratumab [plasma membrane]
(Mus musculus)
PDGFRA:olaratumab [plasma membrane]
(Rattus norvegicus)
PDGFRA:olaratumab [plasma membrane]
(Sus scrofa)
PDGFRA:olaratumab [plasma membrane]
(Xenopus tropicalis)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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