IPs transport between nucleus and cytosol

Stable Identifier
R-HSA-1855170
Type
Pathway
Species
Homo sapiens
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Inositol phosphates (IPs) synthesised in the nucleus are imported into the cytosol from the nucleus. The molecular details of these transport processes remain uncertain (Nalaskowski et al. 2002; Ho et al. 2002, Brehm et al. 2007, Saiardi et al. 2001, Saiardi et al. 2000, Fridy et al. 2007, Leslie et al. 2002).

Literature References
PubMed ID Title Journal Year
10827188 The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis

Saiardi, A, Caffrey, JJ, Snyder, SH, Shears, SB

J Biol Chem 2000
17705785 Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase

Brehm, MA, Schenk, TM, Zhou, X, Fanick, W, Lin, H, Windhorst, S, Nalaskowski, MM, Kobras, M, Shears, SB, Mayr, GW

Biochem J 2007
12121577 Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases

Leslie, NR, McLennan, AG, Safrany, ST

BMC Biochem 2002
11502751 Identification and characterization of a novel inositol hexakisphosphate kinase

Saiardi, A, Nagata, E, Luo, HR, Snowman, AM, Snyder, SH

J Biol Chem 2001
11909533 Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase

Ho, MW, Yang, X, Carew, MA, Zhang, T, Hua, L, Kwon, YU, Chung, SK, Adelt, S, Vogel, G, Riley, AM, Potter, BV, Shears, SB

Curr Biol 2002
17690096 Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases

Fridy, PC, Otto, JC, Dollins, DE, York, JD

J Biol Chem 2007
12027805 The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization

Nalaskowski, MM, Deschermeier, C, Fanick, W, Mayr, GW

Biochem J 2002
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