IPs transport between ER lumen and cytosol

Stable Identifier
R-HSA-1855215
Type
Pathway
Species
Homo sapiens
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Inositol phosphates IP3 and IP5 are imported into the cytosol from the endoplasmic reticulum (ER) lumen (Caffrey et al. 1999, Chi et al. 1999, Nalaskowski et al. 2002, Ho et al. 2002, Brehm et al. 2007). The molecular details of these transport processes remain uncertain.

Literature References
PubMed ID Title Journal Year
10087200 Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19

Chi, H, Tiller, GE, Dasouki, MJ, Romano, PR, Wang, J, O'keefe, RJ, Puzas, JE, Rosier, RN, Reynolds, PR

Genomics 1999
17705785 Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase

Brehm, MA, Schenk, TM, Zhou, X, Fanick, W, Lin, H, Windhorst, S, Nalaskowski, MM, Kobras, M, Shears, SB, Mayr, GW

Biochem J 2007
9923613 The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification

Caffrey, JJ, Hidaka, K, Matsuda, M, Hirata, M, Shears, SB

FEBS Lett 1999
11909533 Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase

Ho, MW, Yang, X, Carew, MA, Zhang, T, Hua, L, Kwon, YU, Chung, SK, Adelt, S, Vogel, G, Riley, AM, Potter, BV, Shears, SB

Curr Biol 2002
12027805 The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization

Nalaskowski, MM, Deschermeier, C, Fanick, W, Mayr, GW

Biochem J 2002
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