I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen

Stable Identifier
R-HSA-1855200
Type
Reaction
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
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I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen
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In the endoplasmic reticulum (ER) lumen, multiple inositol polyphosphate phosphatase 1 (MINPP1) dephosphorylates inositol 1,3,4,5-tetrakisphosphate (I(1,3,4,5)P4) to inositol 1,4,5-trisphosphate (I(1,4,5)P3) (Caffrey et al. 1999, Chi et al. 1999).

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as an event of
Catalyst Activity

inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity of MINPP1 [endoplasmic reticulum lumen]

Physical Entity
MINPP1 [endoplasmic reticulum lumen] (Homo sapiens)
Activity
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity (GO:0051717)
Orthologous Events
I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Bos taurus)
I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Danio rerio)
I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Dictyostelium discoideum)
I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Drosophila melanogaster)
I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Mus musculus)
I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Rattus norvegicus)
I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Sus scrofa)
I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Xenopus tropicalis)
Authored
Williams, MG  (2011-10-28)
Reviewed
Wundenberg, T  (2012-11-06)
Created
Williams, MG  (2011-10-28)
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