I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen

Stable Identifier
R-HSA-1855200
Type
Reaction
Species
Homo sapiens
Compartment
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In the endoplasmic reticulum (ER) lumen, multiple inositol polyphosphate phosphatase 1 (MINPP1) dephosphorylates inositol 1,3,4,5-tetrakisphosphate (I(1,3,4,5)P4) to inositol 1,4,5-trisphosphate (I(1,4,5)P3) (Caffrey et al. 1999, Chi et al. 1999).

Literature References
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Participates
Catalyst Activity

inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity of MINPP1 [endoplasmic reticulum lumen]

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