LRRFIP1(1-249)-p-FGFR1(429-822) fusion [cytosol]

Stable Identifier
R-HSA-1839002
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
LRRFIP1-p-2Y-FGFR1 fusion, t(2;8) LRRFIP1-p-FGFR1 fusion
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
19369959 LRRFIP1, a new FGFR1 partner gene associated with 8p11 myeloproliferative syndrome

Soler, G, Nusbaum, S, Varet, B, Macintyre, EA, Vekemans, M, Romana, SP, Radford-Weiss, I

Leukemia 2009
External Reference Information
External Reference
UniProt:Q32MZ4 LRRFIP1
Gene Names
LRRFIP1, GCF2, TRIP
Chain
initiator methionine:1, chain:2-808
Reference Genes
BioGPS Gene:9208 LRRFIP1
COSMIC - genes:LRRFIP1 LRRFIP1
CTD Gene:9208 LRRFIP1
dbSNP Gene:9208 LRRFIP1
ENSEMBL:ENSG00000124831 LRRFIP1
HGNC:6702 LRRFIP1
KEGG:hsa:9208 LRRFIP1
Monarch:9208 LRRFIP1
NCBI Gene:9208 LRRFIP1
OMIM:603256 LRRFIP1
UCSC:Q32MZ4 LRRFIP1
Reference Transcript
Participates
as a component of
Other forms of this molecule
LRRFIP1(1-249)-FGFR1(429-822) fusion [cytosol]
LRRFIP1 [cytosol]
Modified Residues
Name
Insertion of residues 429 to 822 at 250 from UniProt:P11362 FGFR1
Coordinate
250
Name
O4'-phospho-L-tyrosine at 766
Coordinate
766
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
subacute leukemia DOID:3264
myelodysplastic myeloproliferative cancer DOID:4972 Myeloproliferative/Myelodysplastic syndromes, unclassifiable myelodysplastic myeloproliferative disease, Unclassifiable Myeloproliferative/Myelodysplastic syndrome, Myelodysplastic/myeloproliferative disease (morphologic abnormality)
acute lymphocytic leukemia DOID:9952
Cross References
RefSeq
ENSEMBL
OpenTargets
Mondo
GeneCards
HPA
PRO
Pharos - Targets
GlyGen
PDB
Interactors (3)
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