Phosphorylation of EGFR by SRC kinase

Stable Identifier
R-HSA-177937
Type
Reaction
Species
Homo sapiens
Compartment
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Besides autophosphorylation, EGFR can become tyrosine-phosphorylated by the action of the proto-oncogene tyrosine-protein kinase, c-src. This Src homology 2 (SH2) domain-containing protein is one of many such proteins which bind to phosphorylated sites on EGFR to affect signal transmission into the cell.

Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of SRC-1 [plasma membrane]

Orthologous Events
Authored
Reviewed
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