GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR

Stable Identifier
R-HSA-177936
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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The tyrosine sites on SHC1 become possible binding sites for the GRB2:SOS1 complex.

Literature References
PubMed ID Title Journal Year
8493579 Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

Chardin, P, Camonis, JH, Gale, NW, Van Aelst, L, Schlessinger, J, Wigler, MH, Bar-Sagi, D

Science 1993
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created