SHP2 can dephosphorylate paxillin, which leads to Csk dissociation from the paxillin-Src complex and Src activation. Src is an SHP2 effector in EGF-stimulated Erk activation and cell migration.
Montagner, A, Yart, A, Dance, M, Perret, B, Salles, JP, Raynal, P
Ren, Y, Meng, S, Mei, L, Zhao, ZJ, Jove, R, Wu, J
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