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MGST2 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-176058
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Microsomal glutathione S-transferase 2
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Aflatoxin activation and detoxification (Homo sapiens)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Homo sapiens)
MGST trimers [endoplasmic reticulum membrane] (Homo sapiens)
MGST2 trimer [endoplasmic reticulum membrane] (Homo sapiens)
MGST2 [endoplasmic reticulum membrane] (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Glutathione conjugation (Homo sapiens)
GST trimers transfer GS from GSH to luminal substrates (Homo sapiens)
MGST trimers [endoplasmic reticulum membrane] (Homo sapiens)
MGST2 trimer [endoplasmic reticulum membrane] (Homo sapiens)
MGST2 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99735 MGST2
Gene Names
MGST2, GST2
Chain
chain:1-147
Reference Genes
BioGPS Gene:4258 MGST2
COSMIC (genes):MGST2 MGST2
CTD Gene:4258 MGST2
dbSNP Gene:4258 MGST2
ENSEMBL:ENSG00000085871 MGST2
ENSEMBL_homo_sapiens_GENE:ENSG00000085871 MGST2
HGNC:7063 MGST2
KEGG Gene (Homo sapiens):4258 MGST2
Monarch:4258 MGST2
NCBI Gene:4258 MGST2
OMIM:601733 MGST2
UCSC:Q99735 MGST2
Reference Transcript
RefSeq:XM_017008213.1 MGST2
RefSeq:NM_001204368.1 MGST2
RefSeq:NM_001204366.1 MGST2
RefSeq:XM_017008211.1 MGST2
RefSeq:XM_017008212.1 MGST2
RefSeq:NM_002413.4 MGST2
Other Identifiers
0006100128
10707
11753715_a_at
16970906
204168_at
2744739
2744740
2744743
2744748
2744752
2744753
2744754
2744755
2744756
2744757
2744769
2744770
2744778
2744779
4258
8097513
820_at
A_23_P110167
AAC51768
AAH25416
AAP88934
AC108053
AC112236
AY341028
BC025416
BG519599
CAG28568
CCDS3749
CCDS56339
CR407640
ENSG00000085871
ENSP00000265498
ENSP00000423008
ENSP00000424278
ENSP00000482639
ENST00000265498
ENST00000503816
ENST00000506797
ENST00000616265
EntrezGene:4258
g4505180_3p_at
GE59413
GE749191
GO:0003674
GO:0004364
GO:0004464
GO:0004602
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005635
GO:0005737
GO:0005783
GO:0005789
GO:0005886
GO:0006629
GO:0006691
GO:0006750
GO:0006790
GO:0006805
GO:0006950
GO:0008047
GO:0008150
GO:0009056
GO:0009058
GO:0010243
GO:0016020
GO:0016021
GO:0016491
GO:0016740
GO:0016765
GO:0016829
GO:0019370
GO:0030234
GO:0031090
GO:0032496
GO:0034641
GO:0043085
GO:0043226
GO:0043231
GO:0044281
GO:0046466
GO:0050729
GO:0051186
GO:0098869
GO:1901687
HGNC:7063
HPA010707
ILMN_1802027
IPR001129
IPR001446
IPR018295
IPR023352
MGST2
MGST2-201
MGST2-203
MGST2-204
MGST2-207
MIM:601733
NM_001204366
NM_001204367
NM_001204368
NM_002413
NP_001191295
NP_001191296
NP_001191297
NP_002404
PF01124
PH_hs_0004676
PR00488
TC04000687.hg
U77604
U77604_at
uc003ihy.4
uc021xse.2
uc021xsf.1
uc062ztb.1
UPI000000128A
UPI0001D3B870
XM_006714221
XM_017008211
XM_017008212
XM_017008213
XP_006714284
XP_016863700
XP_016863701
XP_016863702
XR_001741221
Participant Of
hasComponent
MGST2 trimer [endoplasmic reticulum membrane]
Inferred To
MGST2 [endoplasmic reticulum membrane] (Bos taurus)
MGST2 [endoplasmic reticulum membrane] (Canis familiaris)
MGST2 [endoplasmic reticulum membrane] (Danio rerio)
MGST2 [endoplasmic reticulum membrane] (Gallus gallus)
MGST2 [endoplasmic reticulum membrane] (Mus musculus)
MGST2 [endoplasmic reticulum membrane] (Rattus norvegicus)
MGST2 [endoplasmic reticulum membrane] (Sus scrofa)
MGST2 [endoplasmic reticulum membrane] (Xenopus tropicalis)
Homologues of MGST2 [endoplasmic reticulum membrane] (Danio rerio)
Homologues of MGST2 [endoplasmic reticulum membrane] (Mus musculus)
Cross References
RefSeq
NP_002404.1
,
XP_016863700.1
,
XP_016863702.1
,
NP_001191297.1
,
XP_016863701.1
,
NP_001191295.1
OpenTargets
ENSG00000085871
GeneCards
Q99735
PRO
Q99735
BRENDA (Homo sapiens)
2.5.1.18
HMDB Protein
HMDBP00821
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15836 VAMP3
6
VAMP3 [phagocytic vesicle membrane]
(R-HSA-2029013)
VAMP3 [recycling endosome membrane]
(R-HSA-2029063)
VAMP3 [trans-Golgi network membrane]
(R-HSA-6814624)
VAMP3 [transport vesicle]
(R-HSA-6814625)
VAMP3 [plasma membrane]
(R-HSA-8867599)
VAMP3 [clathrin-coated vesicle membrane]
(R-HSA-8869130)
0.488
2
UniProt:O75396 SEC22B
6
SEC22B [endoplasmic reticulum membrane]
(R-HSA-5688150)
SEC22B [ER to Golgi transport vesicle membrane]
(R-HSA-5688565)
SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688566)
SEC22B [phagocytic vesicle membrane]
(R-HSA-8863938)
SEC22B [transport vesicle]
(R-HSA-6810994)
SEC22B [Golgi membrane]
(R-HSA-6810993)
0.488
2
UniProt:Q96T60 PNKP
1
PNKP [nucleoplasm]
(R-HSA-5649651)
0.488
2
UniProt:Q96BA8 CREB3L1
7
CREB3L1(427-519) [Golgi membrane]
(R-HSA-8874139)
CREB3L1 [Golgi membrane]
(R-HSA-8874155)
CREB3L1(1-426) [Golgi membrane]
(R-HSA-8874153)
CREB3L1 [endoplasmic reticulum membrane]
(R-HSA-8874157)
CREB3L1(1-375) [cytosol]
(R-HSA-8874215)
CREB3L1(376-426) [Golgi membrane]
(R-HSA-8874213)
CREB3L1(1-375) [nucleoplasm]
(R-HSA-8874222)
0.488
2
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