Reactome | MGST2 [endoplasmic reticulum membrane]

MGST2 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-176058

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Microsomal glutathione S-transferase 2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q99735 MGST2

Gene Names

MGST2, GST2

Chain

chain:1-147

Reference Genes

BioGPS Gene:4258 MGST2

COSMIC (genes):MGST2 MGST2

CTD Gene:4258 MGST2

dbSNP Gene:4258 MGST2

ENSEMBL:ENSG00000085871 MGST2

HGNC:7063 MGST2

KEGG:hsa:4258 MGST2

Monarch:4258 MGST2

NCBI Gene:4258 MGST2

OMIM:601733 MGST2

UCSC:Q99735 MGST2

Reference Transcript

Other Identifiers

11753715_a_at

1560264_at

16970906

204168_PM_at

204168_at

2744739

2744740

2744743

2744744

2744748

2744752

2744753

2744754

2744755

2744756

2744757

2744758

2744759

2744769

2744770

2744772

2744778

2744779

2744780

4258

8097513

820_at

A_14_P108069

A_23_P110167

GE59413

GE749191

GO:0003824

GO:0004364

GO:0004464

GO:0004602

GO:0005515

GO:0005635

GO:0005783

GO:0005789

GO:0005886

GO:0006575

GO:0006629

GO:0006691

GO:0006750

GO:0006790

GO:0008047

GO:0016020

GO:0016209

GO:0016491

GO:0016740

GO:0016829

GO:0019370

GO:0032496

GO:0042802

GO:0043226

GO:0043231

GO:0043295

GO:0046466

GO:0050729

GO:0098754

GO:0098772

GO:0098869

HMNXSV003046875

ILMN_1802027

PH_hs_0004676

TC04000687.hg

TC04002230.hg

U77604_at

g4505180_3p_at

Participates

as a component of

MGST2 trimer [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

Mgst2 [endoplasmic reticulum membrane] (Mus musculus)

Mgst2 [endoplasmic reticulum membrane] (Rattus norvegicus)

MGST2 [endoplasmic reticulum membrane] (Bos taurus)

MGST2 [endoplasmic reticulum membrane] (Canis familiaris)

MGST2 [endoplasmic reticulum membrane] (Gallus gallus)

MGST2 [endoplasmic reticulum membrane] (Sus scrofa)

mgst2 [endoplasmic reticulum membrane] (Danio rerio)

mgst2 [endoplasmic reticulum membrane] (Xenopus tropicalis)

mgst [endoplasmic reticulum membrane] (Dictyostelium discoideum)

Cross References

ENSEMBL

ENST00000503816, ENST00000265498, ENST00000616265, ENSP00000424278, ENST00000506797, ENSP00000482639, ENSP00000423008, ENSP00000265498

OpenTargets

ENSG00000085871

IntEnz

2.5.1.18, 4.4.1.20

HPA

ENSG00000085871-MGST2

PRO

Q99735

Pharos - Targets

Q99735

HMDB Protein

HMDBP00821

PDB

6SSW, 6SSU, 6SSR, 6SSS

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96T60 PNKP	1	PNKP [nucleoplasm] (R-HSA-5649651)	0.556	3
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.556	3
UniProt:Q15836 VAMP3	6	VAMP3 [recycling endosome membrane] (R-HSA-2029063) VAMP3 [phagocytic vesicle membrane] (R-HSA-2029013) VAMP3 [plasma membrane] (R-HSA-8867599) VAMP3 [trans-Golgi network membrane] (R-HSA-6814624) VAMP3 [transport vesicle] (R-HSA-6814625) VAMP3 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869130)	0.556	3
UniProt:Q16585 SGCB	3	SGCB [endoplasmic reticulum membrane] (R-HSA-9913185) SGCB [Golgi membrane] (R-HSA-9913180) SGCB [plasma membrane] (R-HSA-9630718)	0.556	3

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